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ChemicalBook >> CAS DataBase List >> KIRENOL

KIRENOL

KIRENOL price.
  • $43 - $2125
  • Product name: KIRENOL
  • CAS: 52659-56-0
  • MF: C20H34O4
  • MW: 338.49
  • EINECS:
  • MDL Number:MFCD00210519
  • Synonyms:(1R,3S,4aS,4bS,7S,10aS)-1,2,3,4,4a,4b,5,6,7,9,10,10a-Dodecahydro-3-hydroxy-7-[(R)-1,2-dihydroxyethyl]-1,4a,7-trimethylphenanthrene-1-methanol;Kirenol;KIRENOL(P);Kirel;1,7-PhenanthrenediMethanol,1,2,3,4,4a,4b,5,6,7,- 9,10,10a-dodecahydro-3-hydroxy-R7- (hydroxyMethyl)-1,4a,7-triMethyl-,(R7R,1R,- 3S,4aS,4bR,7S,10aS)-;1,7-Phenanthrenedimethanol, 1,2,3,4,4a,4b,5,6,7,9,10,10a-dodecahydro-3-hydroxy-α7-(hydroxymethyl)-1,4a,7-trimethyl-, (α7R,1R,3S,4aS,4bR,7S,10aS)-;(1R)-1-[(2S,4aR,4bS,6S,8R,8aS)-6-hydroxy-8-(hydroxymethyl)-2,4b,8-trimethyl-4,4a,5,6,7,8a,9,10-octahydro-3H-phenanthren-2-yl]ethane-1,2-diol;KirenolQ: What is Kirenol Q: What is the CAS Number of Kirenol Q: What is the storage condition of Kirenol Q: What are the applications of Kirenol
75 prices
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Brand
  • aablocks
  • ACHEMBLOCK
  • AK Scientific
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Arctom
  • AvaChem
  • Biorbyt Ltd
  • Biosynth
  • Cayman Chemical
  • Chem-Impex
  • ChemScene
  • Crysdot
  • DC Chemicals
  • JR MediChem
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • TCI Chemical
  • TRC
  • Usbiological
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  • Manufactureraablocks
  • Product numberAA00DEAD
  • Product description(R)-1-((2S,4aR,4bS,6S,8R,8aS)-6-Hydroxy-8-(hydroxymethyl)-2,4b,8-trimethyl-2,3,4,4a,4b,5,6,7,8,8a,9,10-dodecahydrophenanthren-2-yl)ethane-1,2-diol
  • Packaging5mg
  • Price$44
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00DEAD
  • Product description(R)-1-((2S,4aR,4bS,6S,8R,8aS)-6-Hydroxy-8-(hydroxymethyl)-2,4b,8-trimethyl-2,3,4,4a,4b,5,6,7,8,8a,9,10-dodecahydrophenanthren-2-yl)ethane-1,2-diol
  • Packaging10mg
  • Price$50
  • Updated2026-05-28
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  • Manufactureraablocks
  • Product numberAA00DEAD
  • Product description(R)-1-((2S,4aR,4bS,6S,8R,8aS)-6-Hydroxy-8-(hydroxymethyl)-2,4b,8-trimethyl-2,3,4,4a,4b,5,6,7,8,8a,9,10-dodecahydrophenanthren-2-yl)ethane-1,2-diol
  • Packaging25mg
  • Price$65
  • Updated2026-05-28
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  • Manufactureraablocks
  • Product numberAA00DEAD
  • Product description(R)-1-((2S,4aR,4bS,6S,8R,8aS)-6-Hydroxy-8-(hydroxymethyl)-2,4b,8-trimethyl-2,3,4,4a,4b,5,6,7,8,8a,9,10-dodecahydrophenanthren-2-yl)ethane-1,2-diol
  • Packaging100mg
  • Price$111
  • Updated2026-05-28
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  • Manufactureraablocks
  • Product numberAA00DEAD
  • Product description(R)-1-((2S,4aR,4bS,6S,8R,8aS)-6-Hydroxy-8-(hydroxymethyl)-2,4b,8-trimethyl-2,3,4,4a,4b,5,6,7,8,8a,9,10-dodecahydrophenanthren-2-yl)ethane-1,2-diol
  • Packaging50mg
  • Price$83
  • Updated2026-05-28
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  • ManufacturerACHEMBLOCK
  • Product numberU106790
  • Product descriptionKirenol 98.00%
  • Packaging250MG
  • Price$200
  • Updated2026-05-27
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  • ManufacturerACHEMBLOCK
  • Product numberU106790
  • Product descriptionKirenol 98.00%
  • Packaging100MG
  • Price$100
  • Updated2026-05-27
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  • ManufacturerAK Scientific
  • Product numberV1547
  • Product descriptionKirenol
  • Packaging250mg
  • Price$988
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0016323
  • Product descriptionKIRENOL 95.00%
  • Packaging5MG
  • Price$505.6
  • Updated2021-12-16
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  • ManufacturerApexBio Technology
  • Product numberN1303
  • Product descriptionKirenol
  • Packaging20mg
  • Price$110
  • Updated2026-05-06
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  • ManufacturerApexBio Technology
  • Product numberN1303
  • Product descriptionKirenol
  • Packaging20mg
  • Price$200
  • Updated2021-12-16
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  • ManufacturerArctom
  • Product numberSY068911
  • Product descriptionKirenol,98% ≥98%
  • Packaging10mg
  • Price$204.55
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberCFN98867
  • Product descriptionKirenol ≥98%
  • Packaging20mg
  • Price$128
  • Updated2021-12-16
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  • ManufacturerArctom
  • Product numberAB0687
  • Product descriptionKirenol 98%(HPLC)
  • Packaging20mg
  • Price$132
  • Updated2026-05-26
  • Buy
  • ManufacturerArctom
  • Product numberSLK-S9297
  • Product descriptionKirenol 99.82%
  • Packaging1mg
  • Price$121
  • Updated2026-05-26
  • Buy
  • ManufacturerArctom
  • Product numberAB0687
  • Product descriptionKirenol 98%(HPLC)
  • Packaging1000mg
  • Price$423
  • Updated2026-05-26
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA00DEAD (R)-1-((2S,4aR,4bS,6S,8R,8aS)-6-Hydroxy-8-(hydroxymethyl)-2,4b,8-trimethyl-2,3,4,4a,4b,5,6,7,8,8a,9,10-dodecahydrophenanthren-2-yl)ethane-1,2-diol 5mg $44 2026-05-28 Buy
aablocks AA00DEAD (R)-1-((2S,4aR,4bS,6S,8R,8aS)-6-Hydroxy-8-(hydroxymethyl)-2,4b,8-trimethyl-2,3,4,4a,4b,5,6,7,8,8a,9,10-dodecahydrophenanthren-2-yl)ethane-1,2-diol 10mg $50 2026-05-28 Buy
aablocks AA00DEAD (R)-1-((2S,4aR,4bS,6S,8R,8aS)-6-Hydroxy-8-(hydroxymethyl)-2,4b,8-trimethyl-2,3,4,4a,4b,5,6,7,8,8a,9,10-dodecahydrophenanthren-2-yl)ethane-1,2-diol 25mg $65 2026-05-28 Buy
aablocks AA00DEAD (R)-1-((2S,4aR,4bS,6S,8R,8aS)-6-Hydroxy-8-(hydroxymethyl)-2,4b,8-trimethyl-2,3,4,4a,4b,5,6,7,8,8a,9,10-dodecahydrophenanthren-2-yl)ethane-1,2-diol 100mg $111 2026-05-28 Buy
aablocks AA00DEAD (R)-1-((2S,4aR,4bS,6S,8R,8aS)-6-Hydroxy-8-(hydroxymethyl)-2,4b,8-trimethyl-2,3,4,4a,4b,5,6,7,8,8a,9,10-dodecahydrophenanthren-2-yl)ethane-1,2-diol 50mg $83 2026-05-28 Buy
ACHEMBLOCK U106790 Kirenol 98.00% 250MG $200 2026-05-27 Buy
ACHEMBLOCK U106790 Kirenol 98.00% 100MG $100 2026-05-27 Buy
AK Scientific V1547 Kirenol 250mg $988 2021-12-16 Buy
American Custom Chemicals Corporation API0016323 KIRENOL 95.00% 5MG $505.6 2021-12-16 Buy
ApexBio Technology N1303 Kirenol 20mg $110 2026-05-06 Buy
ApexBio Technology N1303 Kirenol 20mg $200 2021-12-16 Buy
Arctom SY068911 Kirenol,98% ≥98% 10mg $204.55 2021-12-16 Buy
Arctom CFN98867 Kirenol ≥98% 20mg $128 2021-12-16 Buy
Arctom AB0687 Kirenol 98%(HPLC) 20mg $132 2026-05-26 Buy
Arctom SLK-S9297 Kirenol 99.82% 1mg $121 2026-05-26 Buy
Arctom AB0687 Kirenol 98%(HPLC) 1000mg $423 2026-05-26 Buy

Properties

Melting point :197.0 to 201.0 °C
Boiling point :516.9±35.0 °C(Predicted)
Density :1.17±0.1 g/cm3(Predicted)
storage temp. :-20°C Freezer
solubility :Ethanol (Slightly), Methanol (Slightly)
form :Solid
pka :14.06±0.20(Predicted)
color :White to Light Yellow
Major Application :food and beverages
Cosmetics Ingredients Functions :ANTIMICROBIAL
HAIR CONDITIONING
SKIN CONDITIONING - EMOLLIENT
ANTIOXIDANT InChI :InChI=1/C20H34O4/c1-18(17(24)11-21)7-6-15-13(8-18)4-5-16-19(2,12-22)9-14(23)10-20(15,16)3/h8,14-17,21-24H,4-7,9-12H2,1-3H3/t14-,15-,16-,17+,18+,19+,20+/s3
InChIKey :NRYNTARIOIRWAB-QNOIMPALNA-N
SMILES :C[C@@]12C[C@H](O)C[C@@](C)(CO)[C@@]1([H])CCC1=C[C@@](C)([C@@H](O)CO)CC[C@@]21[H] |&1:1,3,6,10,16,18,24,r|
CAS DataBase Reference :52659-56-0

Safety Information

Symbol(GHS): Exclamation Mark (GHS07)
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Kirenol is a diterpenoid that has been found in S. orientalis and has diverse biological activities, including anti-arthritic and anti-inflammatory properties. It inhibits Gram-positive and Gram-negative bacterial growth in disc diffusion assays with MICs ranging from 39 to 156 and 312.5 to 625 μg/ml, respectively. Kirenol also reduces K652 chronic myeloid leukemia cell viability with a 48 hour IC50 value of 18.19 μg/ml and induces apoptosis. In vivo, kirenol (2 mg/kg, p.o.) reduces motor deficit, delays disease onset by approximately five days, and downregulates inflammatory CD4+IFN-γ+ Th1 cells and CD4+IL-17A+ Th17 cells in a mouse model of experimental autoimmune encephalomyelitis (EAE). Intragastric administration of kirenol (1-4 mg/kg) reduces the arthritis index, NF-kB activity, and paw swelling and increases annexin-1 expression without affecting glucocorticoid receptor α (GRα) expression in the synovium in a rat model of collagen-induced arthritis. Topical administration of kirenol (0.3-0.5% w/w) reduces edema induced by carrageenan, complete Freund''s adjuvant (CFA), and formalin in rats up to 44, 67, and 65%, respectively.

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