甲硫米特
| 中文名稱 | 甲硫米特 |
|---|---|
| 中文同義詞 | 甲硫米特;1-甲基-3-(2-(((5-甲基-1H-咪唑-4-基)甲基)硫基)乙基)硫脲;甲硫米特,10 MM DMSO 溶液 |
| 英文名稱 | Metiamide |
| 英文同義詞 | Metiamide;1-Methyl-3-[2-[[(5-methyl-1H-imidazol-4-yl)methyl]thio]ethyl]thiourea;N-Methyl-N'-[2-[[(5-methyl-1H-imidazol-4-yl)methyl]thio]ethyl]thiourea;SKF-92058;MetiaMide hydrochloride;MetiaMide HCl;N-Methyl-N'-[2-((5-methyl-4-imidazolyl)methylthio)ethyl]thiourea;NSC 307755 |
| CAS號(hào) | 34839-70-8 |
| 分子式 | C9H16N4S2 |
| 分子量 | 244.38 |
| EINECS號(hào) | 200-258-5 |
| 相關(guān)類別 | 抑制劑 |
| Mol文件 | 34839-70-8.mol |
| 結(jié)構(gòu)式 |  |
甲硫米特 性質(zhì)
| 沸點(diǎn) | 463.0±55.0 °C(Predicted) |
|---|---|
| 密度 | 1.245±0.06 g/cm3(Predicted) |
| 儲(chǔ)存條件 | Sealed in dry,Store in freezer, under -20°C |
| 溶解度 | 溶于水 |
| 酸度系數(shù)(pKa) | 14.14±0.10(Predicted) |
| 形態(tài) | 固體 |
| 顏色 | 白色至米白色 |
| InChI | InChI=1S/C9H16N4S2/c1-7-8(13-6-12-7)5-15-4-3-11-9(14)10-2/h6H,3-5H2,1-2H3,(H,12,13)(H2,10,11,14) |
| InChIKey | FPBPLBWLMYGIQR-UHFFFAOYSA-N |
| SMILES | N(C)C(NCCSCC1NC=NC=1C)=S |
Metiamide (SK&F 92058) 是組胺H2受體拮抗劑。
Ki: 0.92 uM (H2 receptor)
Metiamide (SK&F 92058) is a competitive with aldehyde substrates and noncompetitive with the Human E3 Aldehyde Dehydrogenase coenzyme, binding to both the free E3 isozyme and the enzyme·coenzyme binary complex with K i values of 0.92 μM glycolaldehyde as the varied substrate. Data is got as percentage change in GTPase activity induced by metiamide compared with the GTPase activity stimulated by HA (100 μM).
安全信息
| 更新日期 | 產(chǎn)品編號(hào) | 產(chǎn)品名稱 | CAS號(hào) | 包裝 | 價(jià)格 |
|---|---|---|---|---|---|
| 2026/06/05 | HY-15540R | 甲硫米特 Metiamide (Standard) | 34839-70-8 | 1 mg | 1800元 |
| 2026/06/05 | HY-15540 | 甲硫米特 Metiamide | 34839-70-8 | 1 mg | 706元 |