SARDOMOZIDE
| 中文名稱 | SARDOMOZIDE |
|---|---|
| 中文同義詞 | 2-(4-甲脒基-2,3-二氫-1H-茚-1-亞基)肼甲脒;化合物 T12833 |
| 英文名稱 | 4-amidinoindan-1-one 2'-amidinohydrazone |
| 英文同義詞 | (E)-2-(4-carbaMiMidoyl-2,3-dihydro-1H-inden-1-ylidene)hydrazinec;CGP 48664;SAM 486A;2-(4-carbamimidoyl-2,3-dihydro-1H-inden-1-ylidene)hydrazinecarboximidamide;4-amidinoindan-1-one 2'-amidinohydrazone;(E)-2-(4-carbamimidoyl-2,3-dihydro-1H-inden-1-ylidene)hydrazinecarboximidamide;Hydrazinecarboximidamide, 2-[4-(aminoiminomethyl)-2,3-dihydro-1H-inden-1-ylidene]-;Sardomozide (CGP-48664 |
| CAS號 | 149400-88-4 |
| 分子式 | C11H14N6 |
| 分子量 | 230.274 |
| EINECS號 | |
| 相關(guān)類別 | |
| Mol文件 | 149400-88-4.mol |
| 結(jié)構(gòu)式 |  |
SARDOMOZIDE 性質(zhì)
| 沸點 | 438.8±55.0 °C(Predicted) |
|---|---|
| 密度 | 1.54±0.1 g/cm3(Predicted) |
| 儲存條件 | 2-8°C(protect from light) |
| 溶解度 | 溶于二甲基亞砜 |
| 酸度系數(shù)(pKa) | 11.54±0.20(Predicted) |
Sardomozide 是一種 S-腺苷甲硫氨酸脫羧酶 (SAMDC) 抑制劑，其 IC50 值為 5 nM。
IC50: 5 nM (SAMDC)
Sardomozide is a S-adenosylmethionine decarboxylase (SAMDC) inhibitor with an IC 50 of 5 nM in cell assay. Following treatment for 48 h with 3 μM Sardomozide, intracellular SAMDC activity is reduced to 10% of control. When the CHO/664 cells are grown in the presence of Sardomozide and during treatment with DENSPM, vacuole formation is not observed, and these cells are growth-inhibited and contain levels of DENSPM similar to the parental CHO cells.
安全信息
| 更新日期 | 產(chǎn)品編號 | 產(chǎn)品名稱 | CAS號 | 包裝 | 價格 |
|---|---|---|---|---|---|
| 2026/06/05 | HY-13746 | SARDOMOZIDE Sardomozide | 149400-88-4 | 5 mg | 1260元 |
| 2026/06/05 | HY-13746 | SARDOMOZIDE Sardomozide | 149400-88-4 | 10 mM * 1 mL in DMSO | 1386元 |