2-CHLORO-7-(2-DEOXY-4-C-ETHYNYL-Β-D-ERYTHRO-PENTOFURANOSYL)-7H-PYRROLO[2,3-D]PYRIMIDIN-4-AMINE
| 中文名稱 | 2-CHLORO-7-(2-DEOXY-4-C-ETHYNYL-Β-D-ERYTHRO-PENTOFURANOSYL)-7H-PYRROLO[2,3-D]PYRIMIDIN-4-AMINE |
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| 中文同義詞 | MK-8527;化合物 MK-8527;2-氯-7-(2-脫氧-4-C-乙炔基-β-D-赤式-戊呋喃糖基)-7H-吡咯并[2,3-d]嘧啶-4-胺 |
| 英文名稱 | 2-Chloro-7-(2-deoxy-4-C-ethynyl-β-D-erythro-pentofuranosyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine |
| 英文同義詞 | 2-Chloro-7-(2-deoxy-4-C-ethynyl-β-D-erythro-pentofuranosyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine;7H-Pyrrolo[2,3-d]pyrimidin-4-amine, 2-chloro-7-(2-deoxy-4-C-ethynyl-β-D-erythro-pentofuranosyl)-;2-Chloro-7-(2-deoxy-4-C-ethynyl-β-D-erythro-pentofuranosyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine (ACI) |
| CAS號(hào) | 1810869-23-8 |
| 分子式 | C13H13ClN4O3 |
| 分子量 | 308.72 |
| EINECS號(hào) | |
| 相關(guān)類別 | |
| Mol文件 | 1810869-23-8.mol |
| 結(jié)構(gòu)式 | ![2-CHLORO-7-(2-DEOXY-4-C-ETHYNYL-Β-D-ERYTHRO-PENTOFURANOSYL)-7H-PYRROLO[2,3-D]PYRIMIDIN-4-AMINE 結(jié)構(gòu)式](CAS/20240320/GIF/1810869-23-8.gif) |
2-CHLORO-7-(2-DEOXY-4-C-ETHYNYL-Β-D-ERYTHRO-PENTOFURANOSYL)-7H-PYRROLO[2,3-D]PYRIMIDIN-4-AMINE 性質(zhì)
| 密度 | 1.63±0.1 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted) |
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| 酸度系數(shù)(pKa) | 12.67±0.60(predicted) |
| 形態(tài) | Solid |
| 顏色 | White to off-white |
2-CHLORO-7-(2-DEOXY-4-C-ETHYNYL-Β-D-ERYTHRO-PENTOFURANOSYL)-7H-PYRROLO[2,3-D]PYRIMIDIN-4-AMINE 用途與合成方法
MK-8527 是 HIV 抑制劑和核苷逆轉(zhuǎn)錄酶易位抑制劑 (NRTTI)。MK-8527 具有與 ISL (HY-104012) 類似的抑制機(jī)制。