SSTR5 ANTAGONIST 2 TFA
| 中文名稱 | SSTR5 ANTAGONIST 2 TFA |
|---|---|
| 中文同義詞 | 化合物 SSTR5 antagonist 2 TFA |
| 英文名稱 | SSTR5 antagonist 2 TFA |
| 英文同義詞 | SSTR5 antagonist 2 TFA |
| CAS號(hào) | 1254733-98-6 |
| 分子式 | C34H36F4N2O7 |
| 分子量 | 660.66 |
| EINECS號(hào) | |
| 相關(guān)類別 | |
| Mol文件 | 1254733-98-6.mol |
| 結(jié)構(gòu)式 |  |
SSTR5 ANTAGONIST 2 TFA 性質(zhì)
SSTR5 antagonist 2 TFA (compound 10) 是強(qiáng)效的、具有口服活性的生長(zhǎng)激素抑制激素(受體)亞型 5 (SSTR5) 的選擇性拮抗劑，有潛力用于 2 型糖尿病的研究。
SSTR5.
SSTR5 antagonist 2 (10 mg/kg, orally) increases both total and active circulating incretin hormone GLP1 levels in mice at a dose of 10 mg/kg.
SSTR5 antagonist 2 increases pancreatic insulin secretion as well as total and active GLP1 release, and demonstrates synergistic effects in combination with DPP4 inhibitors.
| Animal Model: | Rodent diabetic model without risk of hypoglycemia. |
| Dosage: | 10 mg/kg. |
| Administration: | Orally. |
| Result: | Increased both total and active circulating incretin hormone GLP1 levels. |