乙芐香豆
| 中文名稱 | 乙芐香豆 |
|---|---|
| 中文同義詞 | 乙芐香豆;苯丙香豆素;4-羥基-3-(1-苯基丙基)-2H-苯并吡喃-2-酮;苯丙香豆素(乙芐香豆);苯丙羥基香豆素;乙腈中乙芐香豆;苯丙羥基香豆素,10 MM DMSO 溶液;乙芐香豆|Phenprocoumon |
| 英文名稱 | PHENPROCOUMON |
| 英文同義詞 | PHENPROCOUMON;2H-1-Benzopyran-2-one, 4-hydroxy-3-(1-phenylpropyl)-;3-(1-Phenylpropyl)-4-hydroxycoumarin;3-(1'-Phenyl-propyl)-4-oxycoumarin;3-(alpha-Ethylbenzyl)-4-hydroxycoumarin;4-Hydroxy-3-(1-phenylpropyl)-2H-1-benzopyran-2-one;4-Hydroxy-3-(1-phenylpropyl)-2H-chromen-2-one;Coumarin, 3-(alpha-ethylbenzyl)-4-hydroxy- |
| CAS號(hào) | 435-97-2 |
| 分子式 | C18H16O3 |
| 分子量 | 280.32 |
| EINECS號(hào) | 207-108-9 |
| 相關(guān)類別 | 化工原料 |
| Mol文件 | 435-97-2.mol |
| 結(jié)構(gòu)式 |  |
乙芐香豆 性質(zhì)
| 熔點(diǎn) | 179-180° |
|---|---|
| 沸點(diǎn) | 463.2±45.0 °C(Predicted) |
| 密度 | 1.261±0.06 g/cm3(Predicted) |
| 儲(chǔ)存條件 | 2-8°C |
| 溶解度 | 可溶于氯仿（少許）、甲醇（少許） |
| 形態(tài) | 固體 |
| 酸度系數(shù)(pKa) | 4.50±1.00(Predicted) |
| 顏色 | 白色至類白色 |
| InChI | 1S/C18H16O3/c1-2-13(12-8-4-3-5-9-12)16-17(19)14-10-6-7-11-15(14)21-18(16)20/h3-11,13,20H,2H2,1H3 |
| InChIKey | QNDUUBVQYBBRBW-UHFFFAOYSA-N |
| EPA化學(xué)物質(zhì)信息 | Phenprocoumon (435-97-2) |
Vitamin K.
After a single i.v.-dose of phenprocoumon (0.355 mg/kg) the anticoagulant effect obtained is greater in older than in younger rats. There are no differences between younger and older rats in the rate of elimination, volume of distribution and in the free fraction and free concentration values of phenprocoumon in plasma and liver. After i.v.-injection of 64.3 μg/kg [ 3 H]vitamin K 1 and different doses of phenprocoumon (0.02 to 3 mg/kg) the [ 3 H]vitamin K 1 concentration in the liver decreases and the [ 3 H] vitamin K 1 -2, 3-epoxide concentration increases dependent on the dose and the liver concentration of phenprocoumon. These changes are more pronounced in the older than in the younger rats.
安全信息
| 危險(xiǎn)品運(yùn)輸編號(hào) | 2811 |
|---|---|
| WGK Germany | WGK 3 |
| 危險(xiǎn)等級 | 6.1(b) |
| 包裝類別 | III |
| 存儲(chǔ)類別 | 6.1C - 可燃，急性毒性 類別3 毒性化合物或者引起慢性影響的化合物 |
| 危險(xiǎn)性類別 | 急性毒性 類別3 經(jīng)皮 急性毒性 類別3 吸入 急性毒性 類別3經(jīng)口 生殖毒性 類別2 特異性靶器官毒性-反復(fù)接觸類別2 |
| 毒害物質(zhì)數(shù)據(jù) | 435-97-2(Hazardous Substances Data) |