短桿菌肽
| 中文名稱 | 短桿菌肽 |
|---|---|
| 中文同義詞 | GRAMICIDIN (TECHNICAL GRADE);短桿菌肽 EP標(biāo)準(zhǔn)品;短桿菌肽 USP標(biāo)準(zhǔn)品;VG-16;短桿菌肽A;E2970 GRAMICIDIN FROM BACILLUANEURINOLYTICU短桿菌肽;短桿菌肽/A1A;格拉霉素復(fù)合物 |
| 英文名稱 | GRAMICIDIN |
| 英文同義詞 | gramicidin from bacillus brevis*(gramicidin D);Gramicidin micronized USP23;GramicidinN.F.Xiv;gramicidin from bacillus aneurinolyticus (bacillus brevis);GRAMACIDIN D;GRAMICIDIN;GRAMICIDIN D [DUBOS];Aids002001 |
| CAS號 | 1405-97-6 |
| 分子式 | C99H140N20O17 |
| 分子量 | 1882.2947 |
| EINECS號 | 215-790-4 |
| 相關(guān)類別 | 微生物代謝物;小分子抑制劑;化工;目錄多肽;A - KAntibiotics;Antibacterial;Antibiotics A to;Antibiotics G-MAntibiotics;Chemical Structure Class;Inhibits an EnzymeAntibiotics;Interferes with Cell Membrane Permeability (Ionophores)Antibiotics;Mechanism of Action;Peptides;Spectrum of Activity;PeptidesMulti-Drug Resistance;Substrates for Drug Efflux PumpsMore...Close...;Drug Efflux Pumps |
| Mol文件 | 1405-97-6.mol |
| 結(jié)構(gòu)式 |  |
短桿菌肽 性質(zhì)
| 熔點 | 229-230℃ |
|---|---|
| 儲存條件 | 2-8°C |
| 溶解度 | 幾乎不溶于水，溶于甲醇，微溶于乙醇 |
| 形態(tài) | 固體 |
| 顏色 | 白色至類白色 |
| 水溶解性 | Soluble in acetic acid and lower alcohols. Practically insoluble in water. |
| InChIKey | ZWCXYZRRTRDGQE-SORVKSEFSA-N |
| CAS 數(shù)據(jù)庫 | 1405-97-6 |
Gramicidin 是一種抗菌肽，組裝成膜中的通道并增加其對陽離子的滲透性。
醋酸根含量≤12.0%
水分含量≤8.0%
肽含量≥80.0%
內(nèi)毒素≤50EU/mg
氨基酸組成分析≤±10%
Bacterial
Gramicidin is an antimicrobial peptide assembling as channels in membranes and increasing their permeability towards cations. There is poor Gramicidin activity against E. coli and S. cerevisae as shown from the survival of microbes (%) over a range of Gramicidin concentrations, in contrast with the action of Gramicidin on S. aureus . The microbicidal activity occurs over a range of low Gramicidin and DODAB concentrations which are not toxic to S. cerevisae .
參考質(zhì)量標(biāo)準(zhǔn)
外觀性狀:白色粉末純度(HPLC):≥98.0%醋酸根含量≤12.0%
水分含量≤8.0%
肽含量≥80.0%
內(nèi)毒素≤50EU/mg
氨基酸組成分析≤±10%
安全信息
| 危險品標(biāo)志 | Xn |
|---|---|
| 危險類別碼 | 20/21-36/37/38 |
| 安全說明 | 26-36-24/25-22 |
| WGK Germany | 3 |
| RTECS號 | MD8225000 |
| 海關(guān)編碼 | 2941906000 |
| 存儲類別 | 11 - 可燃固體 |
| 毒性 | mouse,LD50,intravenous,1500ug/kg (1.5mg/kg),Science. Vol. 103, Pg. 419, 1946. |
| 提供商 | 語言 |
|---|---|
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英文
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