1430218-51-1
| 中文名稱 | 1430218-51-1 |
|---|---|
| 中文同義詞 | 化合物 T17234;化合物 VI 16832;I型激酶抑制劑(VI 16832) |
| 英文名稱 | VI16832 |
| 英文同義詞 | VI16832;Pyrido[2,3-d]pyrimidin-7(8H)-one, 2-[[4-(2-aminoethoxy)phenyl]amino]-8-bicyclo[2.2.1]hept-2-yl- |
| CAS號(hào) | 1430218-51-1 |
| 分子式 | C22H25N5O2 |
| 分子量 | 391.47 |
| EINECS號(hào) | |
| 相關(guān)類(lèi)別 | 細(xì)胞生物學(xué)試劑 |
| Mol文件 | 1430218-51-1.mol |
| 結(jié)構(gòu)式 |  |
1430218-51-1 性質(zhì)
| 沸點(diǎn) | 611.9±65.0 °C(Predicted) |
|---|---|
| 密度 | 1.337±0.06 g/cm3(Predicted) |
| 儲(chǔ)存條件 | Store at -20°C |
| 溶解度 | 二甲基亞砜：83.3 mg/mL（212.79 mM） |
| 形態(tài) | 固體 |
| 酸度系數(shù)(pKa) | 8.57±0.10(Predicted) |
| 顏色 | 淺黃至黃色 |
VI 16832 是一種廣譜的 I 型激酶抑制劑，可用作不同癌細(xì)胞系中蛋白激酶比較表達(dá)分析的富集工具。
Type I kinase
VI 16832 is a broad spectrum Type I kinase inhibitor. Phosphoproteomics analysis of VI 16832-enriched fractions from MV4-11, HCT116, or 435S cells results in more than 8500 phosphopeptide identifications. These translate into almost 1700 distinct phosphopeptide species derived from 212 different members of the protein kinase superfamily. Analysis of VI 16832-retained proteins from the three cancer cell lines considerably increases the overall number of identified phosphorylation sites on protein kinases. Considering the sum of all phosphopeptide intensities as a measure for VI 16832-enriched protein amount, more than 80% is derived from protein kinases.
安全信息
| 更新日期 | 產(chǎn)品編號(hào) | 產(chǎn)品名稱 | CAS號(hào) | 包裝 | 價(jià)格 |
|---|---|---|---|---|---|
| 2026/06/05 | HY-18623 | 1430218-51-1 VI 16832 | 1430218-51-1 | 1mg | 990元 |
| 2026/06/05 | HY-18623 | 1430218-51-1 VI 16832 | 1430218-51-1 | 5mg | 3150元 |