Pyrido[2,3-d]pyrimidin-7(8H)-one, 6-acetyl-8-cyclopentyl-2-[[5-(4-hydroxy-1-piperazinyl)-2-pyridinyl]amino]-5-methyl- 基本信息
| 中文名稱 | Pyrido[2,3-d]pyrimidin-7(8H)-one, 6-acetyl-8-cyclopentyl-2-[[5-(4-hydroxy-1-piperazinyl)-2-pyridinyl]amino]-5-methyl- |
|---|---|
| 中文同義詞 | 哌柏西利雜質(zhì)CHPP;帕博西尼雜質(zhì)C;哌柏西利羥胺衍生物雜質(zhì);帕布昔利布22;6-乙?；?8-環(huán)戊基-2-((5-(4-羥基哌嗪-1-基)吡啶-2-基)氨基)-5-甲基吡啶[2,3-D]嘧啶-7(8H)-酮(帕布昔利布雜質(zhì));帕布昔利布(帕博西尼)雜質(zhì)92;哌柏西利雜質(zhì)J;哌柏西利 IMP11 |
| 英文名稱 | Pyrido[2,3-d]pyrimidin-7(8H)-one, 6-acetyl-8-cyclopentyl-2-[[5-(4-hydroxy-1-piperazinyl)-2-pyridinyl]amino]-5-methyl- |
| 英文同義詞 | Pyrido[2,3-d]pyrimidin-7(8H)-one, 6-acetyl-8-cyclopentyl-2-[[5-(4-hydroxy-1-piperazinyl)-2-pyridinyl]amino]-5-methyl-;6-acetyl-8-cyclopentyl-2-((5-(4-hydroxypiperazin-1-yl)pyridin-2-yl)amino)-5-methylpyrido[2,3-d]pyrimidin-7(8H)-one;N-Hydroxy Palbociclib;6-Acetyl-8-cyclopentyl-2-((5-(4-hydroxypiperazin-1-yl)pyridin-2-yl)amino)-5-methylpyrido[2,3-d]pyrimidin-7(8H)-one (Palbociclib Impurity);6-acetyl-8-cyclopentyl-5-methyl-2-((5-(4-oxo-4l4-piperazin-1-yl)pyridin-2-yl)amino)pyrido[2,3-d]pyrimidin-7(8H)-one |
| CAS號 | 2231085-26-8 |
| 分子式 | C24H29N7O3 |
| 分子量 | 463.53 |
| EINECS號 | |
| 相關(guān)類別 | 雜質(zhì)對照品 |
| Mol文件 | 2231085-26-8.mol |
| 結(jié)構(gòu)式 | ![Pyrido[2,3-d]pyrimidin-7(8H)-one, 6-acetyl-8-cyclopentyl-2-[[5-(4-hydroxy-1-piperazinyl)-2-pyridinyl]amino]-5-methyl- 結(jié)構(gòu)式](CAS/20200119/GIF/2231085-26-8.gif) |
Pyrido[2,3-d]pyrimidin-7(8H)-one, 6-acetyl-8-cyclopentyl-2-[[5-(4-hydroxy-1-piperazinyl)-2-pyridinyl]amino]-5-methyl- 性質(zhì)
| 熔點 | >200°C (dec.) |
|---|---|
| 沸點 | 742.2±70.0 °C(Predicted) |
| 密度 | 1.393±0.06 g/cm3(Predicted) |
| 儲存條件 | -20°C Freezer, Under inert atmosphere |
| 溶解度 | 可溶于DMSO（少許）、甲醇（少許） |
| 酸度系數(shù)(pKa) | 12.88±0.20(Predicted) |
| 形態(tài) | 固體 |
| 顏色 | 淺黃色至厚黃色 |