原花青素B1
| 中文名稱 | 原花青素B1 |
|---|---|
| 中文同義詞 | 原花青素B1(95%);原花青素 B1, 來(lái)源于葡萄籽;原花青素B1;原矢車(chē)菊素B1;原花青素B1(標(biāo)準(zhǔn)品);順式,反式′′-4,8′′-二-(3,3′,4′,5,7-五羥基黃烷);原花青素(OPC);原花青素B1對(duì)照品 |
| 英文名稱 | Procyanidin B1 |
| 英文同義詞 | Procyanidin B1 [Epicatechin (4β→8) catechin];PROCYANIDIN B1;CIS,TRANS''-4,8''-BI-(3,3',4',5,7-PENTAHYDROXYFLAVANE);EPICATECHIN(4B-8)CATECHIN;EPICATECHIN(4BETA->8)CATECHIN;(2R,2'R,3R,3'S,4R)-2,2'-Bis(3,4-dihydroxyphenyl)-4,8'-bichroman-3,3',5,5',7,7'-hexol;(2R,2'R,3R,3'S,4β)-3,3',4,4'-Tetrahydro-2α,2'α-bis(3,4-dihydroxyphenyl)-4,8'-bi[2H-1-benzopyran]-3,3',5,5',7,7'-hexol;(2R,3R,4R,2'R,3'S)-2,2'-Bis(3,4-dihydroxyphenyl)-3,3',4,4'-tetrahydro-4,8'-bi(2H-1-benzopyran)-3,3',5,5',7,7'-hexol |
| CAS號(hào) | 20315-25-7 |
| 分子式 | C30H26O12 |
| 分子量 | 578.52 |
| EINECS號(hào) | |
| 植物來(lái)源 | 葡萄籽 |
| 相關(guān)類別 | 中藥對(duì)照品;標(biāo)準(zhǔn)品;植物提取物;對(duì)照品;植提標(biāo)準(zhǔn)品;花青素標(biāo)準(zhǔn)品;標(biāo)準(zhǔn)品-中藥標(biāo)準(zhǔn)品;標(biāo)準(zhǔn)品-對(duì)照品;天然植物提取物;Catechins & Tannins;chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract;標(biāo)準(zhǔn)品 -中藥標(biāo)準(zhǔn)品;標(biāo)準(zhǔn)品，對(duì)照品;醫(yī)藥、農(nóng)藥及染料中間體 |
| Mol文件 | 20315-25-7.mol |
| 結(jié)構(gòu)式 |  |
原花青素B1 性質(zhì)
| 熔點(diǎn) | 231～232℃ |
|---|---|
| 沸點(diǎn) | 955.3±65.0 °C(Predicted) |
| 密度 | 1.705±0.06 g/cm3(Predicted) |
| 儲(chǔ)存條件 | Inert atmosphere,2-8°C |
| 溶解度 | 丙酮（微溶）、乙醇（微溶）、甲醇（微溶）、水（微溶） |
| 酸度系數(shù)(pKa) | 9.29±0.60(Predicted) |
| 形態(tài) | 固體 |
| 顏色 | 淺棕色 |
| 主要應(yīng)用 | food and beverages |
| InChIKey | XFZJEEAOWLFHDH-UKWJTHFESA-N |
| SMILES | [C@H]1(C2=CC=C(O)C(O)=C2)OC2=CC(O)=CC(O)=C2[C@H](C2=C3O[C@H](C4=CC=C(O)C(O)=C4)[C@@H](O)CC3=C(O)C=C2O)[C@H]1O |
| LogP | 0.300 (est) |
Procyanidin B1 is a polyphenolic flavonoid isolated from fruits and fruit juices, binds to TLR4/MD-2 complex, and has anti-inflammatory activity. Procyanidin B1 causes cellular toxicity at concentrations >100 μg/mL. Procyanidin B1 (100 μg/mL) inhibits LPS-induced TNF-α production, and expression of MD-2, TRAF6, NF-κB mRNA, phosphorylated p38 MAPK and NF-κB protein in THP1 cells. Procyanidin B1 (50-100 μM) protects against Aβ oligomer-induced neuronal death. Procyanidin B1 potently inhibits the activation of caspase-3 at 100 μM, caspase-8 at concentrations of 30, 50, and 100 μM and caspase-9 at concentrations of 10, 30, 50, and 100 μM. Procyanidin B1 (10, 20, 30 μM) significantly and dose-dependently induces expression of ACO and CPT1, with no obvious effect on mRNA expression of PPARα.
藥理藥效:抗氧活性、抑制腫瘤作用。
原花青素B1是一種B型原花青素，存在于錫蘭肉桂中，具有抗炎，抗氧化，抗腫瘤，保護(hù)心血管的作用。
| 提供商 | 語(yǔ)言 |
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| 更新日期 | 產(chǎn)品編號(hào) | 產(chǎn)品名稱 | CAS號(hào) | 包裝 | 價(jià)格 |
|---|---|---|---|---|---|
| 2025/12/22 | HY-N0795 | 原花青素B1 Procyanidin B1 | 20315-25-7 | 1mg | 600元 |
| 2025/12/22 | HY-N0795 | 原花青素B1 Procyanidin B1 | 20315-25-7 | 5mg | 1200元 |