142479-62-7
| 中文名稱 | 142479-62-7 |
|---|---|
| 中文同義詞 | 化合物GLUTEN EXORPHIN C;谷蛋白外啡肽C;五肽Gluten Exorphin C;谷朊粉阿片肽Gluten Exorphin C |
| 英文名稱 | DELTA-OPIOID RECEPTOR PEPTIDE TRIFLUOROACETATE SALT |
| 英文同義詞 | TYR-PRO-ILE-SER-LEU TRIFLUOROACETATE SALT;exorphin c;EXORPHIN C TRIFLUOROACETATE SALT;DELTA-OPIOID RECEPTOR PEPTIDE TRIFLUOROACETATE SALT;exorphin C trifluoroacetate;L-Leucine, L-tyrosyl-L-prolyl-L-isoleucyl-L-seryl-;H-YPISL-OH;inhibit,Gluten Exorphin C,Inhibitor,Opioid Receptor |
| CAS號 | 142479-62-7 |
| 分子式 | C29H45N5O8 |
| 分子量 | 591.7 |
| EINECS號 | |
| 相關(guān)類別 | 標(biāo)準(zhǔn)品 |
| Mol文件 | 142479-62-7.mol |
| 結(jié)構(gòu)式 |  |
142479-62-7 性質(zhì)
| 沸點(diǎn) | 969.3±65.0 °C(Predicted) |
|---|---|
| 密度 | 1.264±0.06 g/cm3(Predicted) |
| 儲存條件 | −20°C |
| 溶解度 | 溶于二甲基亞砜 |
| 酸度系數(shù)(pKa) | 3.30±0.10(Predicted) |
| 形態(tài) | 固體 |
| 顏色 | 白色至米白色 |
| 序列 | Tyr-Pro-Ile-Ser-Leu |
IC50: 40 μM (μ opioid), 13.5 μM (δ opioid)
Gluten exorphin C, a novel opioid peptide, is isolated from the pepsin-trypsin-chymotrypsin digest of wheat gluten. Gluten exorphin C is evaluated its opioid activities by the GPI and MVD assays and its receptor affinities by radioreceptor assays. Its IC 50 s are 40 μM and 13.5 μM in the GPI and the MVD assays, respectively. Gluten exorphin C has a structure quite different from any of the endogenous and exogenous opioid peptides ever reported in that the N terminal Tyr is the only aromatic amino acid. The analogs containing Tyr-Pro-X-Ser-Leu are synthesized to study its structure-activity relationship. Peptides in which X is an aromatic amino acid or an aliphatic hydrophobic amino acid has opioid activity.
安全信息
| WGK Germany | 3 |
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| 提供商 | 語言 |
|---|---|
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英文
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| 更新日期 | 產(chǎn)品編號 | 產(chǎn)品名稱 | CAS號 | 包裝 | 價格 |
|---|---|---|---|---|---|
| 2026/06/05 | HY-P1596 | 142479-62-7 Gluten Exorphin C | 142479-62-7 | 1 mg | 500元 |
| 2026/06/05 | HY-P1596 | 142479-62-7 Gluten Exorphin C | 142479-62-7 | 5 mg | 1200元 |