酚嘧啶 撲蟯靈
| 中文名稱 | 酚嘧啶 撲蟯靈 |
|---|---|
| 中文同義詞 | 含 4,4′-亞甲基雙(3-羥基-2-萘甲酸) 的 1-甲基-2-(3-羥基苯乙烯基)-1,4,5,6-四氫嘧啶化合物;酚嘧啶 撲蟯靈;酚嘧啶;奧克太;牛津猩猩;(E)-3-(2-(1-甲基-1,4,5,6-四氫嘧啶-2-基)乙烯基)苯酚 4,4'-亞甲基雙(3-羥基-2-萘甲酸) (1:1);酚嘧啶撲蟯靈,10 MM DMSO 溶液;(E)-3-(2-(1-甲基-1,4,5,6-四氫嘧啶-2-基)乙烯基)苯酚 4,4'-亞甲基雙(3-羥基-2-萘甲酸) (1:1) |
| 英文名稱 | OXANTEL PAMOATE |
| 英文同義詞 | 2-Naphthalenecarboxylic acid, 4,4-methylenebis3-hydroxy-, compd. with 3-(1E)-2-(1,4,5,6-tetrahydro-1-methyl-2-pyrimidinyl)ethenylphenol (1:1);1-methyl-2-(3-hydroxyphenylethenyl)-1,4,5,6-tetrahydropyrimidine compound with 4,4'-methylenebis(3-hydroxy-2-naphthoic acid);4,4'-Methylenebis(3-hydroxy-2-naphthoic) acid, compound with (E)-3-(2-(1,4,5,6-tetrahydro-1-methylpyrimidin-2-yl)vinyl)phenol (1:1);Einecs 272-332-6;Phenol, 3-(2-(1,4,5,6-tetrahydro-1-methyl-2-pyrimidinyl)ethenyl), (E)-, 4,4'-methylenebis(3-hydroxy-2-naphthalenecarboxylate) (1:1) (salt);1-METHYL-2-[3-HYDROXYPHENYLETHENYL]-1,4,5,6-TETRAHYDROPYRIMIDINE COMPOUND WITH 4,4'-METHYLENEBIS[3-HYDROXY-2-NAPHTHOIC ACID];OXANTEL PAMOATE;4,4'-methylenebis[3-hydroxy-2-naphthoic] acid, compound with (E)-3-[2-(1,4,5,6-tetrahydro-1-methylpyrimidin-2-yl)vinyl]phenol (1:1) |
| CAS號 | 68813-55-8 |
| 分子式 | C49H48N4O8 |
| 分子量 | 820.93 |
| EINECS號 | 272-332-6 |
| 相關類別 | 小分子抑制劑;醫(yī)藥原料;有機中間體;Aromatics;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;MOTILIUM |
| Mol文件 | 68813-55-8.mol |
| 結構式 |  |
酚嘧啶 撲蟯靈 性質
| 熔點 | >224°C (dec.) |
|---|---|
| 儲存條件 | Amber Vial, Refrigerator, Under inert atmosphere |
| 溶解度 | 可溶于DMSO（略微加熱）、甲醇（略微加熱） |
| 形態(tài) | 固體 |
| 顏色 | 白色至類白色 |
| 主要應用 | forensics and toxicology pharmaceutical (small molecule) veterinary |
| InChIKey | WSYDAPQDBDVYIO-QEFJDTIGSA-N |
| SMILES | CN1CCCN=C1\C=C\c2cccc(O)c2.OC(=O)c3cc4ccccc4c(Cc5c(O)c(cc6ccccc56)C(O)=O)c3O |
Antiparasitic
The activity of the veterinary drug Oxantel pamoate is studied against Trichuris muris , Ancylostoma ceylanicum and Necator americanus . An ED 50 s of 4.7 mg/kg is calculated for Oxantel pamoate against T. muris in mice. Combinations of Oxantel pamoate with pyrantel pamoate behaved antagonistically (combination index (CI)=2.53). Oxantel pamoate combined with Levamisole, Albendazole or Ivermectin using ratios based on their ED 50 s reveals antagonistic effects (CI=1.27, 1.90 and 1.27, respectively). A highly synergistic effect (CI=0.15) is observed when Oxantel pamoate-mebendazole is administered to T. muris -infected mice. Oxantel pamoate (10 mg/kg) lacks activity against Ancylostoma ceylanicum and Necator americanus .
安全信息
| WGK Germany | 3 |
|---|---|
| 存儲類別 | 11 - 可燃固體 |
| 提供商 | 語言 |
|---|---|
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英文
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| 更新日期 | 產(chǎn)品編號 | 產(chǎn)品名稱 | CAS號 | 包裝 | 價格 |
|---|---|---|---|---|---|
| 2026/06/05 | HY-B1344R | 酚嘧啶 撲蟯靈 Oxantel pamoate (Standard) | 68813-55-8 | 50 mg | 350元 |
| 2026/06/05 | HY-B1344 | 酚嘧啶 撲蟯靈 Oxantel pamoate | 68813-55-8 | 50 mg | 154元 |