NH2-MPAA-NODA
| 中文名稱 | NH2-MPAA-NODA |
|---|---|
| 中文同義詞 | 化合物 NH2-MPAA-NODA |
| 英文名稱 | NH2-MPAA-NODA |
| 英文同義詞 | NH2-MPAA-NODA |
| CAS號(hào) | |
| 分子式 | |
| 分子量 | 0 |
| EINECS號(hào) | |
| 相關(guān)類別 | 大環(huán)化合物 |
| Mol文件 | Mol File |
| 結(jié)構(gòu)式 |
NH2-MPAA-NODA 性質(zhì)
| 形態(tài) | 固體 |
|---|---|
| 顏色 | 淺黃至黃色 |
NH2-MPAA-NODA 是一種基于硝基的可光裂解的 linker，它有一個(gè) NODA 修飾單元和一個(gè) MPAA 主鏈。NH2-MPAA-NODA 可以通過(guò)標(biāo)記 18F-氟化物來(lái)用作放射性標(biāo)簽。
IC50: Nitroveratryl-based photocleavable linker
NH2-MPAA-NODA contains the 1,4,7-triazacyclononane-1,4-diacetate (NODA) motif with a methyl phenyl acetic acid (MPAA) backbone, and it has enough ability to form stable Al18F-chelates. The organ of luoroaluminates are easily accessible from the reaction of 1 and AlF3.NH2-MPAA-NODA can be conjugated to some inhibitors/antagonists labeled with 18 F for PET imaging of targeting tumors. It also can be used as a radiolabel of peptides