吡拉唑酸
| 中文名稱 | 吡拉唑酸 |
|---|---|
| 中文同義詞 | 吡拉唑酸;化合物 T12484 |
| 英文名稱 | pirazolac |
| 英文同義詞 | pirazolac;1-(4-Fluorophenyl)-4-(4-chlorophenyl)-1H-pyrazole-3-acetic acid;4-(4-Chlorophenyl)-1-(4-fluorophenyl)-1H-pyrazole-3-acetic acid;ZK-76604;1H-Pyrazole-3-acetic acid, 4-(4-chlorophenyl)-1-(4-fluorophenyl)- |
| CAS號(hào) | 71002-09-0 |
| 分子式 | C17H12ClFN2O2 |
| 分子量 | 330.74 |
| EINECS號(hào) | 2751023 |
| 相關(guān)類別 | |
| Mol文件 | 71002-09-0.mol |
| 結(jié)構(gòu)式 |  |
吡拉唑酸 性質(zhì)
| 熔點(diǎn) | 148-149°; mp 135-136° |
|---|---|
| 沸點(diǎn) | 520.8±50.0 °C(Predicted) |
| 密度 | 1.36±0.1 g/cm3(Predicted) |
| 儲(chǔ)存條件 | Store at -20°C |
| 溶解度 | 溶于二甲基亞砜 |
| 酸度系數(shù)(pKa) | 3.94±0.10(Predicted) |
Pirazolac 是一種非甾體抗炎藥。
Pirazolac is a non-steroidal anti-inflammatory drug. Pirazolac concentration-relatedly inhibits the accumulation of prostanoids in incubates of human gastric mucosa, but this inhibition is less than that by indomethacin and other commonly used non-steroidal anti-inflammatory drugs. This difference may explain the claim that Pirazolac is less damaging to the stomach.