3-[4-Hydroxy-3-(5,6,7,8-tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)phenyl]-2-propenoicacid
生物活性靶點(diǎn)體外研究 用途與合成方法 MSDS 3-[4-Hydroxy-3-(5,6,7,8-tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)phenyl]-2-propenoicacid價(jià)格(試劑級) 上下游產(chǎn)品信息
| 中文名稱 | 3-[4-Hydroxy-3-(5,6,7,8-tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)phenyl]-2-propenoicacid |
|---|---|
| 中文同義詞 | 化合物 T14912;CD 3254,RXRΑ激動(dòng)劑;化合物 CD3254;化合物CD3254,10 MM DMSO 溶液;CD3254 |CAS 196961-43-0;3- [4-羥基-3-(5,6,7,8-四氫-3,5,5,8,8-五甲基-2-萘基)苯基] -2-丙烯酸;3- [4-羥基-3-（5,6,7,8-四氫-3,5,5,8,8-五甲基-2-萘基）苯基] -2-丙烯酸;3-[4-羥基-3-(5,6,7,8-四氫-3,5,5,8,8-五甲基-2-萘基)苯基] -2-丙酸 |
| 英文名稱 | 3-[4-Hydroxy-3-(5,6,7,8-tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)phenyl]-2-propenoicacid |
| 英文同義詞 | 3-[4-Hydroxy-3-(5,6,7,8-tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)phenyl]-2-propenoicacid;CD 3254;2-Propenoic acid, 3-[4-hydroxy-3-(5,6,7,8-tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)phenyl]-;CD3254,CD-3254;CD3254, 10 mM in DMSO |
| CAS號 | 196961-43-0 |
| 分子式 | C24H28O3 |
| 分子量 | 364.48 |
| EINECS號 | |
| 相關(guān)類別 | |
| Mol文件 | 196961-43-0.mol |
| 結(jié)構(gòu)式 | ![3-[4-Hydroxy-3-(5,6,7,8-tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)phenyl]-2-propenoicacid 結(jié)構(gòu)式](CAS/GIF/196961-43-0.gif) |
3-[4-Hydroxy-3-(5,6,7,8-tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)phenyl]-2-propenoicacid 性質(zhì)
| 熔點(diǎn) | 165 - 167°C |
|---|---|
| 沸點(diǎn) | 508.0±50.0 °C(Predicted) |
| 密度 | 1.108±0.06 g/cm3(Predicted) |
| 儲(chǔ)存條件 | Store at -20°C |
| 溶解度 | 可溶于DMSO（少許）、甲醇（少許） |
| 形態(tài) | 固體 |
| 酸度系數(shù)(pKa) | 4.61±0.10(Predicted) |
| 顏色 | 白色至類白色 |
3-[4-Hydroxy-3-(5,6,7,8-tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)phenyl]-2-propenoicacid 用途與合成方法
CD3254 是一種有效的選擇性類視黃醇 X 受體 (RXR) 激動(dòng)劑。
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RXR
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CD3254 induces similar phenotypes of malformations after 5 days exposure at low concentration (20 μg/L) to those after the 1st d exposure at high concentrations (50 and 100 μg/L).
Cell Viability Assay
| Cell Line: | zebrafish ( Danio rerio ) embryos |
| Concentration: | 10, 20, 50, 100 μg/L |
| Incubation Time: | |
| Result: | The percent of survival decreased by 19.1 % in 100 μg/L CD3254-treated group after the 1st day exposure. The embryos did not hatch in groups exposed to 100 μg/L CD3254 for 5 days or to 1 mg/L CD3254 for the 1st day. |
安全信息
| 更新日期 | 產(chǎn)品編號 | 產(chǎn)品名稱 | CAS號 | 包裝 | 價(jià)格 |
|---|---|---|---|---|---|
| 2026/06/05 | HY-107399 | CD3254 | 196961-43-0 | 1 mg | 454元 |
| 2026/06/05 | HY-107399 | 3-[4-Hydroxy-3-(5,6,7,8-tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)phenyl]-2-propenoicacid CD3254 | 196961-43-0 | 5mg | 1000元 |