Isocoptisine acetate
| 中文名稱 | Isocoptisine acetate |
|---|---|
| 中文同義詞 | 異黃連堿(乙酸鹽);化合物 T12570;異黃連堿乙酸鹽 Pseudocoptisine acetate;異黃連堿乙酸鹽 Pseudocoptisine acetate |
| 英文名稱 | Isocoptisine acetate |
| 英文同義詞 | Isocoptisine acetate;Pseudocoptisine acetate |
| CAS號 | 30426-66-5 |
| 分子式 | C21H17NO6 |
| 分子量 | 379.37 |
| EINECS號 | |
| 相關類別 | 標準品 |
| Mol文件 | 30426-66-5.mol |
| 結(jié)構(gòu)式 |  |
Isocoptisine acetate 性質(zhì)
| 熔點 | 146-147 °C |
|---|---|
| 儲存條件 | Store at -20°C |
| 溶解度 | 溶于二甲基亞砜 |
Pseudocoptisine (0, 60, 90 μM; 1 hour) dose-dependently inhibited LPS-induced NO production in RAW264.7 cells.
Pseudocoptisine (30-90 μM; 1 hour; RAW264.7 cells) significantly reduces the LPS-induced TNF-α and IL-6 production and their mRNA expressions.
Pseudocoptisine acetate reduces levels of the pro-inflammatory mediators, such as, iNOS, COX-2, TNF-alpha, and IL-6 through the inhibition of NF-kappaB activation via the suppression of ERK and p38 phosphorylation in RAW 264.7 cells.
The anti-amnesic activities of Pseudocoptisine in mice on the learning and memory impairments induced by scopolamine (1.0 mg/kg, i.p.) are examined. Pseudocoptisine (2.0 mg/kg, p.o.) significantly reverses cognitive impairments in mice by passive avoidance test.
安全信息
| 更新日期 | 產(chǎn)品編號 | 產(chǎn)品名稱 | CAS號 | 包裝 | 價格 |
|---|---|---|---|---|---|
| 2023/03/20 | HY-N6894 | Isocoptisine acetate Pseudocoptisine acetate | 30426-66-5 | 1mg | 7240元 |
| 2023/03/20 | HY-N6894 | Isocoptisine acetate Pseudocoptisine acetate | 30426-66-5 | 5mg | 21710元 |