四甲基若丹明甲酯酸銨
| 中文名稱 | 四甲基若丹明甲酯酸銨 |
|---|---|
| 中文同義詞 | 四甲基羅丹明甲酯;四甲基羅丹明甲酯高氯酸鹽;四甲基若丹明甲酯酸銨;四甲基若丹明甲酯高氯酸鹽;羅丹明甲酯高氯酸鹽;TMRM[四甲基羅丹明甲酯];3,6-雙(二甲基氨基)-9-(2-(甲氧羰基)苯基)黃質高氯酸鹽;3,6-雙(二甲氨基)-9-(2-(甲氧基羰基)苯基)氧雜蒽鎓 高氯酸鹽 |
| 英文名稱 | TETRAMETHYLRHODAMINE METHYL ESTER PERCHLORATE |
| 英文同義詞 | TMRM, PERCHLORATE;TETRAMETHYLRHODAMINE METHYL ESTER PERCHLORATE;Tetramethylrhodamin methylester perchlorate;XanthyliuM, 3,6-bis(diMethylaMino)-9-[2-(Methoxycarbonyl)phenyl]-, perchlorate (1:1);3,6-bis(diMethylaMino)-9-(2-(Methoxycarbonyl)phenyl)xanthyliuM perchlorate;T 668;TMRM [TetraMethylrhodaMine, Methyl ester, perchlorate];TMRM [Tetramethylrhodamine methyl ester] *CAS#: 115532-50-8* |
| CAS號 | 115532-50-8 |
| 分子式 | C25H25ClN2O7 |
| 分子量 | 500.93 |
| EINECS號 | |
| 相關類別 | 熒光探針,標記,顆粒和染色;Xanthene |
| Mol文件 | 115532-50-8.mol |
| 結構式 | ![]() |
四甲基若丹明甲酯酸銨 性質
| 熔點 | 274–276℃ |
|---|---|
| 儲存條件 | Sealed in dry,Room Temperature |
| 溶解度 | 可溶于DMSO |
| 形態(tài) | 晶體 |
| 顏色 | 深綠色 |
| 外觀 | Solid Powder |
| 最大波長(λmax) | 549 nm |
| BRN | 7162165 |
| 主要應用 | diagnostic assay manufacturing hematology histology |
| 生物領域應用 | Detecting mitochondrial membrane potential; apoptosis assays; multidrug resistance assays |
| InChI | 1S/C25H25N2O3.ClHO4/c1-26(2)16-10-12-20-22(14-16)30-23-15-17(27(3)4)11-13-21(23)24(20)18-8-6-7-9-19(18)25(28)29-5;2-1(3,4)5/h6-15H,1-5H3;(H,2,3,4,5)/q+1;/p-1 |
| InChIKey | PFYWPQMAWCYNGW-UHFFFAOYSA-M |
| SMILES | [O-]Cl(=O)(=O)=O.COC(=O)c1ccccc1C2=C3C=C\C(C=C3Oc4cc(ccc24)N(C)C)=[N+](\C)C |
TMRM Perchlorate is a fluorescent probe (excitation, 530±21 nm; emission, 592±22 nm). The fluorescence signal in the presence of TMRM Perchlorate shows a slight decrease after the addition of glutamate, indicative of increased polarization of the mitochondrial inner membrane. In the presence of TMRM Perchlorate (2 μM) the coupled respiration with Complex I substrates or upon the addition of Complex II substrate is decreased by 27%. Exposure of hippocampal cultures to low concentrations of TMRM Perchlorate (50 to 500 nM) for 1 to 3 hours results in selective staining of mitochondria in both neurons and the underlying glial cells. Exposure of hippocampal cultures to high concentrations of TMRM Perchlorate (1 to 25 μM) stains mitochondria selectively and quickly, reaching a plateau after 5 to 10 min. Low concentrations of TMRM Perchlorate (50 to 200 nM) do not induce apoptosis, whereas higher concentrations (0.5 and 2.5 μM) enhance apoptosis (K D =?500 nM).
| 提供商 | 語言 |
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| 更新日期 | 產(chǎn)品編號 | 產(chǎn)品名稱 | CAS號 | 包裝 | 價格 |
|---|---|---|---|---|---|
| 2026/06/06 | T3608 | 四甲基羅丹明甲酯高氯酸鹽 Tetramethylrhodamine Methyl Ester Perchlorate | 115532-50-8 | 10mg | 190元 |
| 2026/06/06 | T3608 | 四甲基羅丹明甲酯高氯酸鹽 Tetramethylrhodamine Methyl Ester Perchlorate | 115532-50-8 | 50mg | 690元 |
