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1008951-10-7

1008951-10-7 Structure

1008951-10-7 Structure
IdentificationBack Directory
[Name]

4-(furan-2-ylmethylamino)diazinane-3,6-dione
[CAS]

1008951-10-7
[Synonyms]

ALKBH5 inhibitor 6
4-(furan-2-ylmethylamino)diazinane-3,6-dione
3,6-Pyridazinedione, 4-[(2-furanylmethyl)amino]tetrahydro-
[Molecular Formula]

C9H11N3O3
[MOL File]

1008951-10-7.mol
[Molecular Weight]

209.2
Chemical PropertiesBack Directory
[Boiling point ]

501.5±45.0 °C(Predicted)
[density ]

1.36±0.1 g/cm3(Predicted)
[pka]

10.80±0.40(Predicted)
Hazard InformationBack Directory
[Uses]

ALKBH5-IN-2 (compound 6) is a potent ALKBH5 inhibitor with an IC50 value of 0.79 μM. ALKBH5-IN-2 inhibits cell viability[1].
[References]

[1] Selberg S, et al. Rational Design of Novel Anticancer Small-Molecule RNA m6A Demethylase ALKBH5 Inhibitors. ACS Omega. 2021 May 14;6(20):13310-13320. DOI:10.1021/acsomega.1c01289
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