| Identification | Back Directory | [Name]
glidobactin C | [CAS]
108351-52-6 | [Synonyms]
BU-2867TC
glidobactin C
Antibioti BU-2867TC
Antibiotic BU-2867TC
(2E,4E)-N-[(1S,2R)-2-Hydroxy-1-[[[[(3E,5S,8S,10S)-10-hydroxy-5-methyl-2,7-dioxo-1,6-diazacyclododeca-3-en]-8-yl]amino]carbonyl]propyl]-2,4-tetradecadienamide | [Molecular Formula]
C29H48N4O6 | [MOL File]
108351-52-6.mol | [Molecular Weight]
548.72 |
| Hazard Information | Back Directory | [Uses]
Glidobactin C (GlbC) is an anti-tumor antibiotic. Glidobactin C (GlbC) has the activity against pathogenic fungi and yeast. Glidobactin C has anti-Candida albicans and Aspergillus fumigatus activity with a MIC of 0.8 μg/mL. Glidobactin C also extends the survival of mice inoculated with leukemia P388 cells[1]. | [References]
[1] Atul Pawar, et al. Competitive Metabolite Profiling of Natural Products Reveals Subunit Specific Inhibitors of the 20S Proteasome. ACS Cent Sci. 2020 Feb 26;6(2):241-246. |
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