| Identification | Back Directory | [Name]
Nimbidiol | [CAS]
113332-25-5 | [Synonyms]
Nimbidiol
(+)-Nimbidiol
Nimbidiol >=95% (LC/MS-ELSD)
9(1H)-Phenanthrenone, 2,3,4,4a,10,10a-hexahydro-6,7-dihydroxy-1,1,4a-trimethyl-, (4aS,10aS)- | [Molecular Formula]
C17H22O3 | [MDL Number]
MFCD24849357 | [MOL File]
113332-25-5.mol | [Molecular Weight]
274.35 |
| Chemical Properties | Back Directory | [Melting point ]
171-175 °C | [Boiling point ]
459.5±45.0 °C(Predicted) | [density ]
1.168±0.06 g/cm3(Predicted) | [storage temp. ]
-20°C | [form ]
solid | [pka]
8.02±0.60(Predicted) | [Major Application]
metabolomics
vitamins, nutraceuticals, and natural products | [InChI]
1S/C17H22O3/c1-16(2)5-4-6-17(3)11-8-14(20)13(19)7-10(11)12(18)9-15(16)17/h7-8,15,19-20H,4-6,9H2,1-3H3/t15?,17-/m1/s1 | [InChIKey]
JMBKXUYCBVKSSY-OMOCHNIRSA-N | [SMILES]
CC1(C)CCC[C@@]2(C)C1CC(=O)c3cc(O)c(O)cc23 |
| Safety Data | Back Directory | [Hazard Codes ]
Xn,N | [Risk Statements ]
22-50 | [Safety Statements ]
61 | [RIDADR ]
UN 3077 9 / PGIII | [WGK Germany ]
3 | [Storage Class]
11 - Combustible Solids | [Hazard Classifications]
Acute Tox. 4 Oral
Aquatic Acute 1
Aquatic Chronic 1 |
| Hazard Information | Back Directory | [Uses]
(+)-Nimbidiol is an anti-angiogenesis agent and a potent intestinal disaccharidase and glucoamylase inhibitor in the treatment of diabetes. | [Biological Activity]
Nimbidiol has an ability to inhibit intestinal glucosidasesincluding maltase-glucoamylasesucrase-isomaltaselactasetrehalase and fungal α-glucosidases. Thusthis bioactive molecule has all the potential to be used as an anti-diabetic drug |
|
| Company Name: |
Energy Chemical
|
| Tel: |
021-58432009 400-005-6266 |
| Website: |
http://www.energy-chemical.com |
| Company Name: |
Merck KGaA
|
| Tel: |
21-20338288 |
| Website: |
www.sigmaaldrich.cn |
|