| Identification | Back Directory | [Name]
1-AMINO-11-AZIDO-3,6,9-TRIOXAUNDECANE | [CAS]
1162336-72-2 | [Synonyms]
N3-TOTA
Azido-C1-PEG3-C3-NH2
11-AZIDO-3,6,9-TRIOXAUNDECAN-1-AMINE
1-Azido-3,6,9-trioxaundecane-11-amine
1-Azido-4,7,10-trioxa-13-tridecanamine
2-[2-[2-(2-Azidoethoxy)ethoxy]ethoxy]ethanamine
2-[2-[2-(2-Azidoethoxy)ethoxy]ethoxy]ethylamine
1-Azido-4,7,10-trioxa-13-tridecanamine≥ 98% (TLC)
3-[2-[2-(3-azidopropoxy)ethoxy]ethoxy]propan-1-amine
3-[2-[2-(3-Azidopropoxy)ethoxy]ethoxy]-1-propanamine | [Molecular Formula]
C8H18N4O3 | [MDL Number]
MFCD23380086 | [MOL File]
1162336-72-2.mol | [Molecular Weight]
218.25 |
| Hazard Information | Back Directory | [Chemical Properties]
1-AMINO-11-AZIDO-3,6,9-TRIOXAUNDECANE is light yellow oil | [Uses]
Azido-C1-PEG3-C3-NH2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Azido-C1-PEG3-C3-NH2 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. | [IC 50]
PEGs | [References]
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
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