| Identification | Back Directory | [Name]
POLY(DEOXYINOSINIC-DEOXYCYTIDYLIC) ACID | [CAS]
118578-37-3 | [Synonyms]
POLY[D(I-C)] SODIUM SALT
POLY[DL-DC] POLY[DL-DC] SODIUM SALT
poly(di-dc) · poly(di-dc) sodium salt
polydeoxyinosinic-deoxycytidylic acid*sodium
Poly(2′-deoxyinosinic-2′-deoxycytidylic acid)
POLYDEOXYINOSINIC-DEOXYCYTIDYLIC ACID SODIUM SALT
POLY(2'-DEOXYINOSINIC-2'-DEOXYCYTIDYLIC AC.)SOSA., 500 UG | [Molecular Formula]
C19H27N7O14P2 | [MDL Number]
MFCD00131970 | [MOL File]
118578-37-3.mol | [Molecular Weight]
639.41 |
| Hazard Information | Back Directory | [Uses]
Poly(deoxyinosinic-deoxycytidylic) acid (Poly(dI-dC) • Poly(dI-dC)) is an alternating copolymer used as a DNA substrate for evaluation of DNA methytransfeases, such as DNA-methyltransferase 1 and as double-stranded DNA model for conformational studies of DNA structure dynamics and drug, small molecule, interactions. | [Uses]
Poly(deoxyinosinic-deoxycytidylic) acid sodium salt has been used in a study that synthesized and characterized bis(2-(pyrimidin-2-γl)ethoxy)alkanes and their pharmacological activity. Poly(deoxyinosinic-deoxycytidylic) acid sodium salt has also been used in a study that investigated the growth of calcium carbonate films on LB/LbL matrices. | [General Description]
Poly (2′-deoxyinosinic-2′-deoxycytidylic acid) sodium salt is an alternating copolymer that acts as a substrate for DNA methyltransferases. | [Biochem/physiol Actions]
Poly(2′-deoxyinosinic-2′-deoxycytidylic acid), poly(dI-dC) is a synthetic DNA substrate. At high salt, Poly(dI-dC) exists in left handed helical conformation and reverts to right-handed form upon decreasing salt. It is used as a non-specific competitor in electrophoretic mobility shift assay (EMSA). |
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