| Chemical Properties | Back Directory | [Boiling point ]
850.9±60.0 °C(Predicted) | [density ]
0.932±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(Predicted) | [solubility ]
DMSO: 20 mg/ml
Ethanol: 25 mg/ml | [pka]
14.17±0.20(Predicted) |
| Hazard Information | Back Directory | [Uses]
C12-113 is a lipidoid delivery agent that can be used to transfect siRNA into cells. C12-113 can also be combined with other lipids to form lipid nanoparticles (LNPs) for the delivery of mRNA encoding the spike glycoprotein of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in mice[1][2]. | [References]
[1] Li J, Song J S, et al. YY1 regulates melanocyte development and function by cooperating with MITF[J]. PLoS genetics, 2012, 8(5): e1002688. DOI:10.1371/journal.pgen.1002688 |
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