| Identification | Back Directory | [Name]
Hexanoic acid, 3-(aminomethyl)-5-methyl-, 2-methylpropyl ester, hydrochloride (1:1), (3S)- | [CAS]
1239692-15-9 | [Synonyms]
Pregabalin Isobutyl Ester Hydrochloride | [Molecular Formula]
C12H26ClNO2 | [MOL File]
1239692-15-9.mol | [Molecular Weight]
251.8 |
| Hazard Information | Back Directory | [Synthesis]
This impurity Hexanoic acid, 3-(aminomethyl)-5-methyl-, 2-methylpropyl ester, hydrochloride (1:1), (3S)- was quantitatively synthesized in the form of hydrochloride salt by the reaction of Pregabalin with thionyl chloride in the presence of isobutanol[1].
| [References]
[1] Sripathi, S., Somesetti, N. R., Veeramalla, R., Challa, N. R., Peddi, S., Karnati, V. R. (2010). Synthesis and characterization of impurities of an anticonvulsant drug, Pregabalin. Arkivoc, 2010 1. https://doi.org/10.3998/ARK.5550190.0011.A22
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