| Identification | Back Directory | [Name]
cortisol 21-sulfate | [CAS]
1253-43-6 | [Synonyms]
Cortisol sulfate
cortisol 21-sulfate
Cortisol 21-(Hydrogen Sulfate)
11β,17α-Dihydroxypregn-4-ene-3,20
Hydrocortisone 21-sulfate potassium salt
11β,17-Dihydroxy-3,20-diketopregn-4-ene-21-yl Sulfate
11β,17α-Dihydroxy-3,20-diketopregn-4-ene-21-yl Sulfate
(11β)-11,17-Dihydroxy-21-(sulfooxy)pregn-4-ene-3,20-dione
Pregn-4-ene-3,20-dione, 11,17-dihydroxy-21-(sulfooxy)-, (11β)- | [Molecular Formula]
C21H30O8S | [MOL File]
1253-43-6.mol | [Molecular Weight]
442.52 |
| Hazard Information | Back Directory | [Uses]
Cortisol 21-Sulfate is a phase II metabolite of Cortisol (H714615). | [Definition]
ChEBI: A steroid sulfate obtained by the formal condensation of hydroxy group at position 21 of cortisol with sulfuric acid. | [in vivo]
Cortisol sulfate (3 mg; i.m.; every other day; for 2-7 weeks) affects behavior through its direct action on the central nervous system[4].
| Animal Model: | Male Wistar-King rats[4] | | Dosage: | 3 mg | | Administration: | Intramuscular injection, every other day, for 2-7 weeks | | Result: | Had significant stimulatory effects on the animal's exploratory behaviors (ambulation and rearing), when the treatments were started soon after weaning (postnatal day 21-24). |
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