| Identification | Back Directory | [Name]
(2S)-6-azido-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}(methyl)amino)hexanoic acid | [CAS]
1263721-14-7 | [Synonyms]
Fmoc-L-MeLys(N3)-OH
6-Azido-N-Fmoc-N-methyl-L-norleucine
(2S)-6-azido-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}(methyl)amino)hexanoic acid | [Molecular Formula]
C22H24N4O4 | [MOL File]
1263721-14-7.mol | [Molecular Weight]
408.46 |
| Hazard Information | Back Directory | [Uses]
Fmoc-L-MeLys(N3)-OH is a click chemistry reagent containing an azide. Fmoc-L-MeLys(N3)-OH is a SPPS building-block for the introduction of N-Me-Lys that can be modified at the N3-group using Click-chemistry[1]. Fmoc-L-MeLys(N3)-OH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. | [References]
[1] Doi T, et al. Solid-phase total synthesis of (-)-apratoxin A and its analogues and their biological evaluation. Chem Asian J. 2011 Jan 3;6(1):180-8. DOI:10.1002/asia.201000549 |
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