| Identification | Back Directory | [Name]
6-Ethyl-3-pyridinamine | [CAS]
126553-00-2 | [Synonyms]
6-Ethyl-3-pyridinamine
6-ethylpyridin-3-amine
2-Ethylpyridin-5-amine
3-Amino-6-ethylpyridine
5-Amino-2-ethylpyridine
3-Pyridinamine, 6-ethyl-
3-Pyridinamine,6-ethyl-(9CI)
6-Ethyl-3-pyridinamine ISO 9001：2015 REACH | [EINECS(EC#)]
604-596-9 | [Molecular Formula]
C7H10N2 | [MDL Number]
MFCD11111131 | [MOL File]
126553-00-2.mol | [Molecular Weight]
122.17 |
| Chemical Properties | Back Directory | [Boiling point ]
244 °C | [density ]
1.037 | [Fp ]
125 °C | [storage temp. ]
Keep in dark place,Inert atmosphere,Room temperature | [pka]
6.83±0.10(Predicted) | [Appearance]
Light yellow to brown Solid-Liquid Mixture |
| Hazard Information | Back Directory | [Synthesis]
The general procedure for the synthesis of 6-ethyl-3-aminopyridine from 5-nitro-2-vinylpyridine is as follows:[Ref. Example 66]; 5-Amino-2-ethylpyridine; 10% palladium-carbon catalyst (50% water moistened, 90 mg) was added to an ethanol solution (30 mL) of 5-nitro-2-vinylpyridine (450 mg), and the reaction was stirred under a hydrogen atmosphere at room temperature for 15 hours. Upon completion of the reaction, the catalyst was removed by filtration. Subsequently, the solvent was evaporated under reduced pressure to afford 6-ethyl-3-aminopyridine as an oily product (359 mg, 98% yield). The product was characterized by 1H-NMR (400 MHz, CDCl3): δ 1.25 (3H, t, J=7.5 Hz), 2.71 (2H, q, J=7.5 Hz), 3.32-3.78 (2H, br), 6.91-6.98 (2H, m), 8.02-8.05 (1H, m). Mass spectrum (ESI) m/z: 123 (M+H)+. | [References]
[1] Patent: EP1591443, 2005, A1. Location in patent: Page/Page column 53 |
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