ChemicalBook--->CAS DataBase List--->130955-37-2

130955-37-2

      130955-37-2 Structure

      130955-37-2 Structure
      IdentificationBack Directory
      [Name]

      m-PEG5-Ms
      [CAS]

      130955-37-2
      [Synonyms]

      PEG4-Oms
      m-PEG5-Ms
      2,5,8,11-Tetraoxatridecan-13-yl methanesulfonate
      2,5,8,11-Tetraoxatridecan-13-ol, 13-methanesulfonate
      [Molecular Formula]

      C10H22O7S
      [MDL Number]

      MFCD30723269
      [MOL File]

      130955-37-2.mol
      [Molecular Weight]

      286.34
      Chemical PropertiesBack Directory
      [storage temp. ]

      Storage temp. 2-8°C
      [form ]

      Liquid
      [color ]

      Colorless to light yellow
      Hazard InformationBack Directory
      [Description]

      m-PEG5-Ms is a PEG linker containing a mesyl group. The mesyl group is a good leaving group for nucleophilic substitution reactions. The hydrophilic PEG spacer increases solubility in aqueous media.
      [Uses]

      m-PEG4-MS is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. m-PEG4-MS is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
      [Biological Activity]

      m-PEG4-Ms is a PROTAC bridge and belongs to the PEG class. m-PEG4-Ms can be used to synthesize a series of PROTAC molecules. It is a cleavable ADC bridge for the synthesis of antibody drug conjugates (ADCs).
      [target]

      Cleavable

      PEGs

      [IC 50]

      Cleavable Linker; PEGs
      [References]

      [1] Sanxing Sun, et al. Triazolotriazine derivatives as a2a receptor antagonists. WO2020002969A1.
      Spectrum DetailBack Directory
      [Spectrum Detail]

      m-PEG5-Ms(130955-37-2)1HNMR
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