ChemicalBook--->CAS DataBase List--->130955-37-2

130955-37-2

130955-37-2 Structure

130955-37-2 Structure
IdentificationBack Directory
[Name]

m-PEG5-Ms
[CAS]

130955-37-2
[Synonyms]

PEG4-Oms
m-PEG5-Ms
2,5,8,11-Tetraoxatridecan-13-yl methanesulfonate
2,5,8,11-Tetraoxatridecan-13-ol, 13-methanesulfonate
[Molecular Formula]

C10H22O7S
[MDL Number]

MFCD30723269
[MOL File]

130955-37-2.mol
[Molecular Weight]

286.34
Chemical PropertiesBack Directory
[storage temp. ]

Storage temp. 2-8°C
[form ]

Liquid
[color ]

Colorless to light yellow
Hazard InformationBack Directory
[Description]

m-PEG5-Ms is a PEG linker containing a mesyl group. The mesyl group is a good leaving group for nucleophilic substitution reactions. The hydrophilic PEG spacer increases solubility in aqueous media.
[Uses]

m-PEG4-MS is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. m-PEG4-MS is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
[Biological Activity]

m-PEG4-Ms is a PROTAC bridge and belongs to the PEG class. m-PEG4-Ms can be used to synthesize a series of PROTAC molecules. It is a cleavable ADC bridge for the synthesis of antibody drug conjugates (ADCs).
[target]

Cleavable

PEGs

[IC 50]

Cleavable Linker; PEGs
[References]

[1] Sanxing Sun, et al. Triazolotriazine derivatives as a2a receptor antagonists. WO2020002969A1.
Spectrum DetailBack Directory
[Spectrum Detail]

m-PEG5-Ms(130955-37-2)1HNMR
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