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130955-37-2

  • 130955-37-2 Structure

    130955-37-2 Structure
    IdentificationBack Directory
    [Name]

    m-PEG5-Ms
    [CAS]

    130955-37-2
    [Synonyms]

    PEG4-Oms
    m-PEG5-Ms
    2,5,8,11-Tetraoxatridecan-13-yl methanesulfonate
    2,5,8,11-Tetraoxatridecan-13-ol, 13-methanesulfonate
    [Molecular Formula]

    C10H22O7S
    [MDL Number]

    MFCD30723269
    [MOL File]

    130955-37-2.mol
    [Molecular Weight]

    286.34
    Chemical PropertiesBack Directory
    [storage temp. ]

    Storage temp. 2-8°C
    [form ]

    Liquid
    [color ]

    Colorless to light yellow
    Hazard InformationBack Directory
    [Description]

    m-PEG5-Ms is a PEG linker containing a mesyl group. The mesyl group is a good leaving group for nucleophilic substitution reactions. The hydrophilic PEG spacer increases solubility in aqueous media.
    [Uses]

    m-PEG4-MS is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. m-PEG4-MS is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
    [Biological Activity]

    m-PEG4-Ms is a PROTAC bridge and belongs to the PEG class. m-PEG4-Ms can be used to synthesize a series of PROTAC molecules. It is a cleavable ADC bridge for the synthesis of antibody drug conjugates (ADCs).
    [target]

    Cleavable

    PEGs

    [IC 50]

    Cleavable Linker; PEGs
    [References]

    [1] Sanxing Sun, et al. Triazolotriazine derivatives as a2a receptor antagonists. WO2020002969A1.
    Spectrum DetailBack Directory
    [Spectrum Detail]

    m-PEG5-Ms(130955-37-2)1HNMR
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