| Identification | Back Directory | [Name]
m-PEG5-Ms | [CAS]
130955-37-2 | [Synonyms]
PEG4-Oms m-PEG5-Ms 2,5,8,11-Tetraoxatridecan-13-yl methanesulfonate 2,5,8,11-Tetraoxatridecan-13-ol, 13-methanesulfonate | [Molecular Formula]
C10H22O7S | [MDL Number]
MFCD30723269 | [MOL File]
130955-37-2.mol | [Molecular Weight]
286.34 |
| Hazard Information | Back Directory | [Description]
m-PEG5-Ms is a PEG linker containing a mesyl group. The mesyl group is a good leaving group for nucleophilic substitution reactions. The hydrophilic PEG spacer increases solubility in aqueous media. | [Uses]
m-PEG4-MS is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. m-PEG4-MS is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. | [Biological Activity]
m-PEG4-Ms is a PROTAC bridge and belongs to the PEG class. m-PEG4-Ms can be used to synthesize a series of PROTAC molecules. It is a cleavable ADC bridge for the synthesis of antibody drug conjugates (ADCs). | [target]
| Cleavable | PEGs | table>[IC 50]
Cleavable Linker; PEGs | [References]
[1] Sanxing Sun, et al. Triazolotriazine derivatives as a2a receptor antagonists. WO2020002969A1. |
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| Company Name: |
T&W GROUP
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| Tel: |
021-61551611 13296011611 |
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www.trustwe.com/ |
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Tags:130955-37-2
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