ChemicalBook--->CAS DataBase List--->132326-74-0

132326-74-0

132326-74-0 Structure

132326-74-0 Structure
IdentificationBack Directory
[Name]

Vesicular Stomatitis Virus Nucleoprotein (52-59)
[CAS]

132326-74-0
[Synonyms]

Vesicular Stomatitis Virus Nucleoprotein (52-59)
L-Leucine, L-arginylglycyl-L-tyrosyl-L-valyl-L-tyrosyl-L-glutaminylglycyl-
[Molecular Formula]

C44H66N12O12
[MOL File]

132326-74-0.mol
[Molecular Weight]

955.07
Chemical PropertiesBack Directory
[Sequence]

Arg-Gly-Tyr-Val-Tyr-Gln-Gly-Leu
Hazard InformationBack Directory
[Uses]

H2-D b restricted epitopes VSV Nucleoprotein (52-59) is a 9-mer peptide derived from the nucleoprotein of Vesicular Stomatitis Virus (VSV). H2-D b restricted epitopes VSV Nucleoprotein (52-59) binds to MHC class I molecules and presents itself to CD8+ T cells, thereby activating cytotoxic T lymphocytes (CTLs), which can recognize and kill cells expressing the corresponding antigen. H2-D b restricted epitopes VSV Nucleoprotein (52-59) can be used in the development of CTL vaccines against Ebola virus[1].
[References]

[1] Herst C V, et al. An effective CTL peptide vaccine for Ebola Zaire Based on Survivors’ CD8+ targeting of a particular nucleocapsid protein epitope with potential implications for COVID-19 vaccine design[J]. Vaccine, 2020, 38(28): 4464-4475. DOI:10.1016/j.vaccine.2020.04.034
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