ChemicalBook--->CAS DataBase List--->134067-56-4

134067-56-4

134067-56-4 Structure

134067-56-4 Structure
IdentificationBack Directory
[Name]

MK 0434
[CAS]

134067-56-4
[Synonyms]

MK434
MK-434
MK 434
MK 0434
MK0434|||MK434|||MK 434|||MK-0434|||MK-434
2H-Indeno[5,4-f]quinolin-2-one, 7-benzoyl-1,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-4a,6a-dimethyl-, (4aR,4bS,6aS,7S,9aS,9bS,11aR)-
[Molecular Formula]

C25H31NO2
[MOL File]

134067-56-4.mol
[Molecular Weight]

377.52
Chemical PropertiesBack Directory
[Boiling point ]

557.0±50.0 °C(Predicted)
[density ]

1.120±0.06 g/cm3(Predicted)
[pka]

14.15±0.70(Predicted)
Hazard InformationBack Directory
[Uses]

MK-0434 is an orally active steroid 5α-reductase inhibitor. MK-0434 specifically inhibits steroid 5α-reductase, thereby reducing the level of dihydrotestosterone (DHT) in the body. MK-0434 can be used in the study of benign prostatic hyperplasia[1].
[References]

[1] Van Hecken, et al. "Plasma concentrations and effect on testosterone metabolism after single doses of MK-0434, a steroid 5 alpha-reductase inhibitor, in healthy subjects." European journal of clinical pharmacology 46 (1994): 123-126. DOI:10.1007/BF00199874
Spectrum DetailBack Directory
[Spectrum Detail]

MK 0434(134067-56-4)1HNMR
134067-56-4 suppliers list
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134067-56-4