| Identification | Back Directory | [Name]
RCS-4 2-methoxy isomer | [CAS]
1345966-76-8 | [Synonyms]
RCS-4 ortho
RCS-4 2-methoxy isomer
(2-methoxyphenyl)-(1-pentylindol-3-yl)methanone
Methanone, (2-methoxyphenyl)(1-pentyl-1H-indol-3-yl)- | [Molecular Formula]
C21H23NO2 | [MOL File]
1345966-76-8.mol | [Molecular Weight]
321.41 |
| Chemical Properties | Back Directory | [Boiling point ]
512.0±30.0 °C(Predicted) | [density ]
1.07±0.1 g/cm3(Predicted) | [solubility ]
DMF: 1 mg/ml; DMSO: 1 mg/ml; Ethanol: 0.3 mg/ml |
| Hazard Information | Back Directory | [Description]
RCS-4 is a synthetic cannabinoid (CB) that has been detected as an adulterant of herbal mixtures. RCS-4 2-methoxy isomer is an analog of RCS-4 that differs only in the location of the methoxy group on the phenyl ring. The affinity of RCS-4 2-methoxy isomer for CB receptors, or its physiological effects, have not been documented. However, RCS-4 2-methoxy isomer structurally resembles JWH 250 , a cannabimimetic indole that shows a high-affinity for both CB1 and CB2 (Ki = 11 and 33 nM, respectively). | [Uses]
RCS-4 is a synthetic cannabinoid (CB) that has been detected as an adulterant of herbal mixtures. RCS-4 2-methoxy isomer is an analog of RCS-4 that differs only in the location of the methoxy group on the phenyl ring. The affinity of RCS-4 2-methoxy isomer for CB receptors, or its physiological effects, have not been documented. However, RCS-4 2-methoxy isomer structurally resembles JWH 250 , a cannabimimetic indole that shows a high-affinity for both CB1 and CB2 (Ki = 11 and 33 nM, respectively).[Cayman Chemical] | [References]
[1] RURI KIKURA-HANAJIRI Yukihiro G Nahoko Uchiyama. Survey of current trends in the abuse of psychotropic substances and plants in Japan[J]. Legal Medicine, 2011, 13 3: Pages 109-115. DOI: 10.1016/j.legalmed.2011.02.003
[2] JOHN W. HUFFMAN . 1-Pentyl-3-phenylacetylindoles, a new class of cannabimimetic indoles[J]. Bioorganic & Medicinal Chemistry Letters, 2005, 15 18: Pages 4110-4113. DOI: 10.1016/j.bmcl.2005.06.008 |
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