| Identification | Back Directory | [Name]
1H-Cyclopenta[b]benzofuran-2-carboxamide, 2,3,3a,8b-tetrahydro-1,8b-dihydroxy-N,6,8-trimethoxy-3a-(4-methoxyphenyl)-3-phenyl-, (1S,2S,3R,3aS,8bR)- | [CAS]
1352914-53-4 | [Synonyms]
1H-Cyclopenta[b]benzofuran-2-carboxamide, 2,3,3a,8b-tetrahydro-1,8b-dihydroxy-N,6,8-trimethoxy-3a-(4-methoxyphenyl)-3-phenyl-, (1S,2S,3R,3aS,8bR)- | [Molecular Formula]
C28H29NO8 | [MOL File]
1352914-53-4.mol | [Molecular Weight]
507.53 |
| Chemical Properties | Back Directory | [density ]
1.356±0.06 g/cm3(Predicted) | [storage temp. ]
4°C, protect from light, stored under nitrogen | [solubility ]
DMSO : 200 mg/mL (394.07 mM; Need ultrasonic) | [form ]
Solid | [pka]
11.66±0.70(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
CR-1-30-B is an inactive enantiomer of CR-1-31-B. CR-1-30-B, as a control, is inactive against eIF4A and has no apparent effect on the induction of MUC1-C translation[1]. | [Biological Activity]
CR-1-30-B is an inactive enantiomer of CR-1-31-B. CR-1-30-B, as a control, is inactive against eIF4A and has no apparent effect on the induction of MUC1-C translation[1]. | [References]
[1]. Jin C, et al. Targeting the eIF4A RNA helicase blocks translation of the MUC1-C oncoprotein [published correction appears in Oncogene. 2021 May;40(18):3347]. Oncogene. 2013;32(17):2179-2188. |
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