ChemicalBook--->CAS DataBase List--->1355327-02-4

1355327-02-4

1355327-02-4 Structure

1355327-02-4 Structure
IdentificationBack Directory
[Name]

ML309 Hydrochloride
[CAS]

1355327-02-4
[Synonyms]

ML309 Hydrochloride
ML309 hydrochloride >=98% (HPLC)
ML309 (hydrochloride),ML 309 (hydrochloride)
[Molecular Formula]

C29H30ClFN4O2
[MDL Number]

MFCD28976192
[MOL File]

1355327-02-4.mol
[Molecular Weight]

521.03
Chemical PropertiesBack Directory
[storage temp. ]

Store at -20°C
[solubility ]

DMSO: soluble
[form ]

A crystalline solid
[color ]

white to beige
Safety DataBack Directory
[Symbol(GHS) ]

Skull and Crossbones (GHS06)
GHS06
[Signal word ]

Danger
[Hazard statements ]

H301
[Precautionary statements ]

P301+P310+P330
[WGK Germany ]

WGK 3
[Storage Class]

6.1C - Combustible acute toxic Cat.3
toxic compounds or compounds which causing chronic effects
[Hazard Classifications]

Acute Tox. 3 Oral
Hazard InformationBack Directory
[Biological Activity]

ML309 is a potent and selective inhibitor of mutant isocitrate dehydrogenase 1 (IDH1) (R132H and R132C) th at binds reversibly the enzyme. ML309 inhibits production of neomorphic 2-hydroxyglutarate in glioblastoma cell line.
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