| Identification | Back Directory | [Name]
4H-Isoxazolo[5,4-d][2]benzazepine-4-acetic acid, 6-(4-chlorophenyl)-1-methyl-, (4S)- | [CAS]
1380089-81-5 | [Synonyms]
CPI-0610 carboxylic acid
CPI 0610 carboxylic acid,CPI0610 carboxylic acid
4H-Isoxazolo[5,4-d][2]benzazepine-4-acetic acid, 6-(4-chlorophenyl)-1-methyl-, (4S)-
(S)-2-(6-(4-chlorophenyl)-1-methyl-4H-benzo[c]isoxazolo[4,5-e]azepin-4-yl)acetic acid | [Molecular Formula]
C20H15ClN2O3 | [MDL Number]
MFCD32201109 | [MOL File]
1380089-81-5.mol | [Molecular Weight]
366.8 |
| Hazard Information | Back Directory | [Uses]
CPI-0610 carboxylic acid is a ligand for target protein for PROTACT. CPI-0610 carboxylic acid is a potent bromodomain and extra-terminal (BET) protein inhibitor. CPI-0610 carboxylic acid has the potential in the therapy of multiple myeloma[1]. | [References]
[1] Albrecht BK, et al. Identification of a Benzoisoxazoloazepine Inhibitor (CPI-0610) of the Bromodomain and Extra-Terminal (BET) Family as a Candidate for Human Clinical Trials. J Med Chem. 2016 Feb 25;59(4):1330-9. DOI:10.1021/acs.jmedchem.5b01882 |
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