| Identification | Back Directory | [Name]
omega-N-allylarginine | [CAS]
139461-37-3 | [Synonyms]
Nω-allyl-L-arginine
omega-N-allylarginine
Nω-Allyl-L-arginine hydrochloride
Nomega-Allyl-L-arginine hydrochloride
L-Ornithine, N5-[imino(2-propen-1-ylamino)methyl]-
Nomega-Allyl-L-arginine hydrochloride, nNOS inhibitor | [Molecular Formula]
C9H18N4O2 | [MOL File]
139461-37-3.mol | [Molecular Weight]
214.26 |
| Hazard Information | Back Directory | [Uses]
Nω-allyl-L-arginine is a competitive and reversible inhibitor of bovine brain nitric oxide synthase (nNOS). Nω-allyl-L-arginine can inactivate nNOS in a time-dependent manner. Nω-allyl-L-arginine also is a substrate, producing L-arginine, acrolein, and H2O[1][2]. | [References]
[1] Zhang HQ, et, al. Mechanism of Inactivation of Neuronal Nitric Oxide Synthase by Nω-Allyl-l-Arginine. J. Am. Chem. Soc. 1997, 119, 45, 10888-10902.
[2] Hah JM, et, al. Deuterium isotope effects and product studies for the oxidation of N(omega)-allyl-L-arginine and N(omega)-allyl-N(omega)-hydroxy-L-arginine by neuronal nitric oxide synthase. Bioorg Med Chem. 2000 Aug;8(8):1931-6. DOI:10.1016/s0968-0896(00)00154-1 |
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Abcam Limited
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