| Identification | Back Directory | [Name]
Ethyl P-hexadecylphosphonofluoridate | [CAS]
1407160-81-9 | [Synonyms]
Ethyl HDFP
Ethyl P-hexadecylphosphonofluoridate | [Molecular Formula]
C18H38FO2P | [MOL File]
1407160-81-9.mol | [Molecular Weight]
336.47 |
| Chemical Properties | Back Directory | [Boiling point ]
404.0±14.0 °C(Predicted) | [density ]
0.930±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(Predicted) | [solubility ]
DMF: 30 mg/ml
DMSO: 20 mg/ml
Ethanol: 30 mg/ml |
| Hazard Information | Back Directory | [Description]
Ethyl HDFP is a lipase inhibitor.1 It inhibits 12 lipases, including fatty acid amide hydrolase (FAAH), fatty acid synthase (FASN), and α/β-hydrolase domain-containing protein 4 (ABHD4), by greater than 75% in mouse T cell hybridoma lysates when used at a concentration of 2 μM. Ethyl HDFP inhibits depalmitoylation of H-Ras in HEK293 cells.WARNING This product is not for human or veterinary use. | [References]
[1] BRENT R MARTIN. Global profiling of dynamic protein palmitoylation[J]. Nature Methods, 2011, 9 1: 84-89. DOI: 10.1038/nmeth.1769 |
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