ChemicalBook--->CAS DataBase List--->1428885-83-9

1428885-83-9

1428885-83-9 Structure

1428885-83-9 Structure
IdentificationBack Directory
[Name]

Glycine, glycyl-L-cysteinyl-L-arginyl-L-α-aspartyl-L-valyl-L-prolyl-L-methionyl-L-seryl-L-methionyl-L-arginylglycylglycyl-L-α-aspartyl-L-arginyl-L-cysteinyl-
[CAS]

1428885-83-9
[Synonyms]

VPM peptide
Glycine, glycyl-L-cysteinyl-L-arginyl-L-α-aspartyl-L-valyl-L-prolyl-L-methionyl-L-seryl-L-methionyl-L-arginylglycylglycyl-L-α-aspartyl-L-arginyl-L-cysteinyl-
[Molecular Formula]

C63H109N25O22S4
[MOL File]

1428885-83-9.mol
[Molecular Weight]

1696.96
Chemical PropertiesBack Directory
[density ]

1.59±0.1 g/cm3(Predicted)
[form ]

Solid
[color ]

White to off-white
Hazard InformationBack Directory
[Uses]

VPM peptide is a dithiol protease-cleavable peptide cross-linker. VPM peptide can be incorporated into the backbone of the PEG-diacrylate (PEG-DA) macromer to form PEG hydrogel[1][2].
[References]

[1] Phelps EA, et, al. Maleimide cross-linked bioactive PEG hydrogel exhibits improved reaction kinetics and cross-linking for cell encapsulation and in situ delivery. Adv Mater. 2012 Jan 3;24(1):64-70, 2 DOI:10.1002/adma.201103574
[2] Foster GA, et, al. Protease-degradable microgels for protein delivery for vascularization. Biomaterials. 2017 Jan;113:170-175. DOI:10.1016/j.biomaterials.2016.10.044
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