| Identification | Back Directory | [Name]
FiMaporfin | [CAS]
1443547-43-0 | [Synonyms]
FiMaporfin
Disulfonated tetraphenyl chlorin | [Molecular Formula]
C132H96N12O18S6 | [MDL Number]
MFCD34469258 | [MOL File]
1443547-43-0.mol | [Molecular Weight]
2330.63 |
| Hazard Information | Back Directory | [Uses]
Fimaporfin (TPCS2a) is a photosensitizer that localizes to endosomes/lysosomes with an excitation wavelength of 420 nm and an emission wavelength between 640 and 680 nm[1][2]. | [References]
[1] Kaja Lund, et al. 5-FU resistant EMT-like pancreatic cancer cells are hypersensitive to photochemical internalization of the novel endoglin-targeting immunotoxin CD105-saporin. J Exp Clin Cancer Res. 2017 Dec 19;36(1):187. DOI:10.1186/s13046-017-0662-6
[2] Enzian P, et al. Photochemical internalization with fimaporfin: enhanced bleomycin treatment for head and neck cancer[J]. Pharmaceutics, 2023, 15(8): 2040. DOI:10.3390/pharmaceutics15082040 |
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