ChemicalBook--->CAS DataBase List--->1443983-36-5

1443983-36-5

1443983-36-5 Structure

1443983-36-5 Structure
IdentificationBack Directory
[Name]

GDC-0927 Racemate
[CAS]

1443983-36-5
[Synonyms]

SRN-927 Racemate
GDC-0927 Racemate
GDC 0927 Racemate,GDC0927 Racemate
2H-1-Benzopyran-6-ol, 2-[4-[2-[3-(fluoromethyl)-1-azetidinyl]ethoxy]phenyl]-3-(3-hydroxyphenyl)-4-methyl-
[Molecular Formula]

C28H28FNO4
[MDL Number]

MFCD31726289
[MOL File]

1443983-36-5.mol
[Molecular Weight]

461.52
Chemical PropertiesBack Directory
[Boiling point ]

664.6±55.0 °C(Predicted)
[density ]

1.257±0.06 g/cm3(Predicted)
[pka]

9.83±0.10(Predicted)
Hazard InformationBack Directory
[Uses]

GDC-0927 Racemate (SRN-927 Racemate) is an estrogen receptor (ER) degrader that can effectively inhibit the activity of ER-α with an IC50 value of 0.2 nM and can be used in diseases related to estrogen receptors.
[References]

[1] Mehmet Kahraman, et al. Estrogen receptor modulator and uses thereof. WO2014205138A1.
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