| Identification | Back Directory | [Name]
HT-2 Toxin-13C22 solution | [CAS]
1486469-92-4 | [Synonyms]
HT-2?Toxin-13C22
HT-2 Toxin-13C22 solution
13C22]-HT-2 toxin-25 μg/mL in ACN | [EINECS(EC#)]
809-031-1 | [Molecular Formula]
13C22H32O8 | [MDL Number]
MFCD11975229 |
| Hazard Information | Back Directory | [Description]
HT-2 toxin-13C22 is intended for use as an internal standard for the quantification of HT-2 toxin (Item No. 20431) by GC- or LC-MS. HT-2 toxin is a type A trichothecene mycotoxin and an active, deacetylated metabolite of the trichothecene mycotoxin T-2 toxin (Item No. 11444).1,2 Like T-2 toxin, HT-2 toxin inhibits protein synthesis and cell proliferation in plants.2 HT-2 toxin also reduces viability of HepG2, A549, HEp-2, Caco-2, A-204, U937, Jurkat, and RPMI-8226 cancer cells with IC50 values ranging from 3.1 to 23 ng/ml and human umbilical vein endothelial cells with an IC50 value of 56.4 ng/ml.1 It induces oxidative stress, DNA damage, and autophagy in, as well as halts the development of, cultured mouse embryos when used at a concentration of 10 nM.3 HT-2 toxin has been found in cereal grains and food products.4,5WARNING This product is not for human or veterinary use. |
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| Company Name: |
ChemeGen
|
| Tel: |
18818260767 |
| Website: |
https://www.chemegen.com |
| Company Name: |
SIGMA-RBI
|
| Tel: |
800 736 3690 (Orders) |
| Website: |
www.sigma-aldrich.com |
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