| Identification | Back Directory | [Name]
[(2R)-2,3-di(octadecanoyloxy)propyl] 2-(2-methoxyethoxycarbonylamino)ethyl phosphate | [CAS]
156543-00-9 | [Synonyms]
| [Molecular Formula]
C45H88NO11P | [MOL File]
156543-00-9.mol | [Molecular Weight]
850.154 |
| Chemical Properties | Back Directory | [solubility ]
Chloroform: 10 mg/ml
DMF: Slightly soluble | [solubility ]
DMSO: Slightly soluble: 0.1-1 mg/mlPBS (pH 7.2): Sparingly soluble: 1-10 mg/ml | [solubility ]
Ethanol: Sparingly soluble: 1-10 mg/ml |
| Hazard Information | Back Directory | [Uses]
18:0 mPEG2000 PE (DSPE-mPEG2000) is a PEG-based phospholipid. 18:0 mPEG2000 PE can be used to synthesis liposomes for delivering cancer agents[1][2]. | [References]
[1] Lainé AL, et al. Conventional versus stealth lipid nanoparticles: formulation and in vivo fate prediction through FRET monitoring. J Control Release. 2014 Aug 28;188:1-8. DOI:10.1016/j.jconrel.2014.05.042
[2] Rathore SS, et al. Effect of surface charge and density of distearylphosphatidylethanolamine-mPEG-2000 (DSPE-mPEG-2000) on the cytotoxicity of liposome-entrapped ricin: effect of lysosomotropic agents. Int J Pharm. 2008 Feb 28;350(1-2):79-94. DOI:10.1016/j.ijpharm.2007.08.032 |
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