| Identification | Back Directory | [Name]
25N-NBOMe (hydrochloride) | [CAS]
1566571-65-0 | [Synonyms]
25N-NBOMe (hydrochloride)
AKAFRJJZBSVSPB-UHFFFAOYSA-N | [Molecular Formula]
C18H23ClN2O5 | [MDL Number]
MFCD30718299 | [MOL File]
1566571-65-0.mol | [Molecular Weight]
382.84 |
| Hazard Information | Back Directory | [Description]
2C-N is described formally as 2,5-dimethoxy-4-nitrophenethylamine and is structurally analogous to the psychedelic drug 2C-B . 2C-N potently stimulates arachidonic acid release through the serotonin receptors 5-HT2C (pEC50 = 5.91) and 5-HT2A (pEC50 = 4.78). 25N-NBOMe is a derivative of 2C-N having an N-(2-methoxybenzyl) addition at the amine. For similar dimethoxyphenethylamines including 2C-B, this N-(2-methoxybenzyl) addition significantly increases activity at the serotonin receptor. This product is intended for forensic and research uses. | [Uses]
25N-NBOMe Hydrochloride is an analog of 25N-NBOMe, a designer drug in the NBOMe category, which is a psychoactive substance associated with abuse and toxicity and has been detected using LC-HRMS in urine samples | [IC 50]
5-HT2A Receptor: 0.144 nM (Ki); 5-HT2C Receptor: 1.06 nM (Ki); 5-HT2B Receptor: 8.7 nM (Ki); 5-HT1A Receptor: 2260 nM (Ki); 5-HT2A Receptor: 0.51 nM (EC50); 5-HT2C Receptor: 1.32 nM (EC50); 5-HT2B Receptor: 47 nM (EC50); 5-HT1A Receptor: 4800 nM (EC50) | [References]
[1] ANDERS ETTRUP. Radiosynthesis and evaluation of 11C-CIMBI-5 as a 5-HT2A receptor agonist radioligand for PET.[J]. Journal of Nuclear Medicine, 2010, 51 11: 1763-1770. DOI: 10.2967/jnumed.109.074021 |
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Biorbyt Ltd.
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+44 (0)1223 859 353 |
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http://www.biorbyt.com |
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