| Identification | Back Directory | [Name]
O-7460 | [CAS]
1572051-31-0 | [Synonyms]
O-7460
O7460,O 7460
ZLEFMXNNQCABDB-SEYXRHQNSA-N
1-((fluoro(methyl)phosphoryl)oxy)-3-isopropoxypropan-2-yl oleate | [Molecular Formula]
C25H48FO5P | [MOL File]
1572051-31-0.mol | [Molecular Weight]
478.618 |
| Chemical Properties | Back Directory | [Boiling point ]
536.5±50.0 °C(Predicted) | [density ]
0.994±0.06 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
Soluble in DMSO | [form ]
Liquid | [color ]
Colorless to light yellow |
| Hazard Information | Back Directory | [Uses]
O-7460 is a selective inhibitor of 2-AG biosynthesis. Dose-dependantly inhibits high-fat diet intake and reduces body weight. | [in vivo]
O-7460 (6-12 mg/kg; a single i.p.) induces a time- and dose-dependent decrease in high-fat diet (HFD) intake and counteracts the body weight increase of mice[1].
O-7460 (12 mg/kg; i.p.) decreases the HFD-caused an up-regulation of 2-AG levels in the hypothalamus and liver of mice[1]. | Animal Model: | Seven-week-old male C57BL/6N inbred mice were administrated high-fat diet (HFD) diet[1] | | Dosage: | 6, 12 mg/kg | | Administration: | A single i.p. | | Result: | Induced a time (30 min, 60 min and 14 h after O-7460 administration) and dose-dependent decrease in HFD intake.
The highest dose significantly counteracted the body weight increase. |
| [storage]
Store at -20°C |
|
| Company Name: |
BOC Sciences
|
| Tel: |
1-631-485-4226; 16314854226 |
| Website: |
https://www.bocsci.com |
| Company Name: |
Energy Chemical
|
| Tel: |
021-58432009 400-005-6266 |
| Website: |
http://www.energy-chemical.com |
| Company Name: |
Boao Pike
|
| Tel: |
010-57798038 15652371397 |
| Website: |
www.biopike.cn |
|