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1594427-18-5

1594427-18-5 Structure

1594427-18-5 Structure
IdentificationBack Directory
[Name]

4-Quinolinecarboxamide, 2-(4-fluorophenyl)-N-[2-(methylamino)ethyl]-
[CAS]

1594427-18-5
[Synonyms]

Viral 2C protein inhibitor 1
4-Quinolinecarboxamide, 2-(4-fluorophenyl)-N-[2-(methylamino)ethyl]-
[Molecular Formula]

C19H18FN3O
[MOL File]

1594427-18-5.mol
[Molecular Weight]

323.36
Chemical PropertiesBack Directory
[Boiling point ]

533.0±50.0 °C(Predicted)
[density ]

1.204±0.06 g/cm3(Predicted)
[pka]

13.29±0.46(Predicted)
Hazard InformationBack Directory
[Uses]

Viral 2C protein inhibitor 1 (compound 6aw) is a potent and broad-spectrum enterovirus antiviral agent, inhibiting viral 2C protein. Viral 2C protein inhibitor 1 inhibits multiple strains of EV-D68, EV-A71 and CVB3 with EC50s of 0.1~3.6 μM, and exhibits high selectivity index and relatively low cytotoxicity[1].
[References]

[1] Musharrafieh R, et al. Development of broad-spectrum enterovirus antivirals based on quinoline scaffold. Bioorg Chem. 2020 Aug;101:103981. DOI:10.1016/j.bioorg.2020.103981
1594427-18-5 suppliers list
Company Name: TargetMol Chemicals Inc.
Tel: +17819995354 , +17819995354
Website:
Company Name: Nantong Hanfang Biotechnology Co. , Ltd.  
Tel: hanfangpharma@126.com 18017580634
Website: hanfangpharma@126.com
Company Name: TargetMol Chemicals Inc.  
Tel: 15002134094
Website: https://www.targetmol.cn/
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