| Identification | Back Directory | [Name]
Boronic acid, B-[5-[[[1-[3-(4-ethoxyphenyl)-3,4-dihydro-4-oxopyrido[2,3-d]pyrimidin-2-yl]ethyl][2-[4-fluoro-3-(trifluoromethyl)phenyl]acetyl]amino]methyl]-2-fluorophenyl]- | [CAS]
1630085-92-5 | [Synonyms]
Boronic acid, B-[5-[[[1-[3-(4-ethoxyphenyl)-3,4-dihydro-4-oxopyrido[2,3-d]pyrimidin-2-yl]ethyl][2-[4-fluoro-3-(trifluoromethyl)phenyl]acetyl]amino]methyl]-2-fluorophenyl]- | [Molecular Formula]
C33H28BF5N4O5 | [MOL File]
1630085-92-5.mol | [Molecular Weight]
666.4 |
| Chemical Properties | Back Directory | [Boiling point ]
821.3±75.0 °C(Predicted) | [density ]
1.36±0.1 g/cm3(Predicted) | [storage temp. ]
-20°C | [solubility ]
DMSO: 2mg/mL, clear | [form ]
powder | [pka]
8.08±0.58(Predicted) | [color ]
white to beige |
| Hazard Information | Back Directory | [Biological Activity]
BD064 is a probe-dependent and biased negative allosteric modulator (NAM) of the chemokine receptor CXCR3 signaling th at preferentially inhibits CXCL11-mediated ?-arrestin 2 recruitment over G protein activation. |
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| Company Name: |
Merck KGaA
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| Tel: |
21-20338288 |
| Website: |
www.sigmaaldrich.cn |
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