| Identification | Back Directory | [Name]
N-desmethylquazepam | [CAS]
1645-32-5 | [Synonyms]
Desalkylquazepam
N-desmethylquazepam
2H-1,4-Benzodiazepine-2-thione, 7-chloro-5-(2-fluorophenyl)-1,3-dihydro- | [Molecular Formula]
C15H10ClFN2S | [MOL File]
1645-32-5.mol | [Molecular Weight]
304.77 |
| Chemical Properties | Back Directory | [Melting point ]
212-214 °C(Solv: water (7732-18-5); chloroform (67-66-3); methanol (67-56-1)) | [Boiling point ]
410.2±55.0 °C(Predicted) | [density ]
1.39±0.1 g/cm3(Predicted) | [solubility ]
DMF: 30 mg/ml; DMSO: 20 mg/ml; Ethanol: Slightly soluble; PBS (pH 7.2): 0.30 mg/ml | [form ]
A crystalline solid | [pka]
9.55±0.40(Predicted) |
| Hazard Information | Back Directory | [Uses]
Desalkylquazepam (Compound 23; N-Desmethylquazepam) is a precursor in the synthesis of triazolobenzodiazepines[1]. | [References]
[1] Hester JB Jr, et al. 6-phenyl-4H-s-triazolo[4,3-a][1,4]benzodiazepines which have central nervous system depressant activity. J Med Chem. 1971 Nov;14(11):1078-81. DOI:10.1021/jm00293a015 |
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