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Chemical PropertiesBack Directory
[Melting point ]

199-200 °C
[Boiling point ]

667.3±55.0 °C(Predicted)
[density ]

1.41±0.1 g/cm3(Predicted)
[pka]

11.05±0.70(Predicted)
Hazard InformationBack Directory
[Uses]

(?)-Acutumine is a tetracyclic chloroalkaloid that exhibits selective cytotoxicity to cultured human T cells and memory-enhancing properties in the Wistar rat model[1].
[Definition]

ChEBI: Acutumine is an alkaloid.
[References]

[1] Kim CY, et al. The chloroalkaloid (-)-acutumine is biosynthesized via a Fe(II)- and 2-oxoglutarate-dependent halogenase in Menispermaceae plants. Nat Commun. 2020 Apr 20;11(1):1867. DOI:10.1038/s41467-020-15777-w
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