| Identification | Back Directory | [Name]
2,4-Pyrimidinediamine, N4-[(4-methyl-2-phenyl-5-thiazolyl)methyl]-N2-(2-methylpropyl)- | [CAS]
1714961-61-1 | [Synonyms]
Antibacterial agent 97 2,4-Pyrimidinediamine, N4-[(4-methyl-2-phenyl-5-thiazolyl)methyl]-N2-(2-methylpropyl)- | [Molecular Formula]
C19H23N5S | [MOL File]
1714961-61-1.mol | [Molecular Weight]
353.48 |
| Hazard Information | Back Directory | [Uses]
Antibacterial agent 97 (hit compound) is a potent antibacterial agent. Antibacterial agent 97 shows antibacterial activities with MIC of 16 and 16 μg/mL for Escherichia coli (E. coli) and Staphylococcus aureus (S. aureus), respectively[1]. | [References]
[1] Fan T, et al. Design, synthesis and evaluation of phenylthiazole and phenylthiophene pyrimidindiamine derivatives targeting the bacterial membrane. Eur J Med Chem. 2020 Mar 15;190:112141. DOI:10.1016/j.ejmech.2020.112141 |
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