| Identification | Back Directory | [Name]
1-O-1'-(Z)-octadecenyl-2-hydroxy-sn-glycero-3-phosphoethanolaMine | [CAS]
174062-73-8 | [Synonyms]
C18(Plasm) LPE
1-O-1'-(Z)-octadecenyl-2-hydroxy-sn-glycero-3-phosphoethanolaMine
1-O-1'-(Z)-OCTADECENYL-2-HYDROXY-SN-GLYCERO-3-PHOSPHOETHANOLAMINE;C18(PLASM) LPE
Phosphoric acid, mono(2-aminoethyl) mono[(2R)-2-hydroxy-3-[(1Z)-1-octadecen-1-yloxy]propyl] ester | [Molecular Formula]
C23H48NO6P | [MDL Number]
MFCD22416833 | [MOL File]
174062-73-8.mol | [Molecular Weight]
465.6 |
| Chemical Properties | Back Directory | [Boiling point ]
581.8±60.0 °C(Predicted) | [density ]
1.048±0.06 g/cm3(Predicted) | [storage temp. ]
-20°C | [solubility ]
Acetonitrile: Slightly Soluble: 0.1-1 mg/ml
DMSO: Slightly Soluble: 0.1-1 mg/ml | [form ]
powder | [pka]
1.15±0.50(Predicted) | [InChIKey]
KACDZDULGKPXHT-HIVNOOBXSA-N | [SMILES]
[O-]P(OCC[N+]([H])([H])[H])(OC[C@]([H])(O)CO/C=C\CCCCCCCCCCCCCCCC)=O |
| Hazard Information | Back Directory | [Uses]
C18(Plasm) LPE (PE(18:1p/0:0)) is a bioactive lipid with the activity of regulating cell signaling and promoting cell growth. C18(Plasm) LPE plays an important role in the composition of cell membranes and has a significant impact on lipid metabolism and cell function. C18(Plasm) LPE is also involved in lipid-mediated cellular responses and improves the adaptability of cells in various physiological and pathological conditions. | [Definition]
ChEBI: 1-(octadec-1-enyl)-sn-glycero-3-phosphoethanolamine is 1-(alk-1-enyl)-sn-glycero-3-phosphoethanolamine in which the alk-1-enyl group is specified as octadec-1-enyl. It is a tautomer of a 1-(octadec-1-enyl)-sn-glycero-3-phosphoethanolamine zwitterion. | [References]
[1] YOON KEUN CHO. Adipocyte lysoplasmalogenase TMEM86A regulates plasmalogen homeostasis and protein kinase A-dependent energy metabolism.[J]. Nature Communications, 2022, 13 1: 4084. DOI: 10.1038/s41467-022-31805-3
[2] YOUJIN CHANG. A targeted metabolomics approach for sepsis-induced ARDS and its subphenotypes.[J]. Critical Care, 2023, 27 1: 263. DOI: 10.1186/s13054-023-04552-0
[3] QING SHEN. Shotgun Lipidomics Strategy for Fast Analysis of Phospholipids in Fisheries Waste and Its Potential in Species Differentiation[J]. Journal of Agricultural and Food Chemistry, 2012, 60 37: 9384-9393. DOI: 10.1021/jf303181s |
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| Company Name: |
Merck KGaA
|
| Tel: |
21-20338288 |
| Website: |
www.sigmaaldrich.cn |
| Company Name: |
Creative Enzymes
|
| Tel: |
1-516-855-7709 |
| Website: |
www.creative-enzymes.com |
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