| Identification | Back Directory | [Name]
2-(2-(2-azidoethoxy)ethoxy)ethyl methanesulfonate | [CAS]
176520-24-4 | [Synonyms]
2-(2-(2-azidoethoxy)ethoxy)ethyl methanesulfonate | [Molecular Formula]
C7H15N3O5S | [MOL File]
176520-24-4.mol | [Molecular Weight]
253.27 |
| Hazard Information | Back Directory | [Uses]
Azido-PEG3-MS is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Azido-PEG3-MS is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. | [IC 50]
PEGs | [References]
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
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